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Protein or Target Summary

Caspase-1

Gene ID834
uniprotP29466
Gene NameCASP1
Ensernbl IDENSP00000433138
FamilyBelongs to the peptidase C14A family.
Sequence
MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN834CASP1Caspase-1P29466
MOUSE12362Casp1Caspase-1P29452
RATCasp1Caspase 1, isoform CRA_bF1LQZ4
RAT25166Casp1Caspase-1Q91W32
RATCasp1Caspase-1P43527

Protein Classes

PANTHER Classes
protein    /    enzyme modulator    /    protease inhibitor    /    Caspase-1
protein    /    enzyme modulator    /    cysteine protease    /    Caspase-1
protein    /    enzyme modulator    /    protease    /    Caspase-1
protein    /    enzyme modulator    /    hydrolase    /    Caspase-1
DTO Classes
protein    /    Enzyme    /    Protease    /    Cysteine protease    /    Caspase-1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source