Description	Caspase-1

Gene and Protein Information

Gene ID	834
Uniprot Accession IDs	B5MDZ1 Q53EY6 Q6DMQ1 Q6GSS3 Q6PI75 Q9UCN3 CASP-1
Ensembl ID	ENSP00000433138
Symbol	IL1BC IL1BCE ICE P45 IL1BC
Family	Belongs to the peptidase C14A family.
Sequence	MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Macaque	706568	CASP1	caspase 1	9544		Inparanoid, OMA, EggNOG
Mouse	12362	Casp1	caspase 1	10090	MGI:96544	Inparanoid, OMA, EggNOG
Rat	25166	Casp1	caspase 1	10116	RGD:2274	Inparanoid, OMA, EggNOG
Horse	100033888	CASP1	caspase 1	9796	VGNC:52358	Inparanoid, OMA
Pig	397319	CASP1	caspase 1, apoptosis-related cysteine peptidase	9823		Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    enzyme modulator    /    protease inhibitor    /    Caspase-1
protein    /    enzyme modulator    /    cysteine protease    /    Caspase-1
protein    /    enzyme modulator    /    protease    /    Caspase-1
protein    /    enzyme modulator    /    hydrolase    /    Caspase-1

DTO Classes
protein / Enzyme / Protease / Cysteine protease / Caspase-1

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Related active small molecules

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

CASP1