| Description | Dual specificity tyrosine-phosphorylation-regulated kinase 1A |
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Gene and Protein Information
| Gene ID | 1859 |
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| Uniprot Accession IDs | O60769 Q92582 Q92810 Q9UNM5 |
| Ensembl ID | ENSP00000381932 |
| Symbol | DYRK MNB MNBH MNB DYRK HP86 MNBH MRD7 DYRK1 |
| Family | Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily. |
| Sequence | MHTGGETSACKPSSVRLAPSFSFHAAGLQMAGQMPHSHQYSDRRQPNISDQQVSALSYSDQIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGGHFTAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSSSTTSSSTSSSSTGNQGNQAYQNRPVAANTLDFGQNGAMDVNLTVYSNPRQETGIAGHPTYQFSANTGPAHYMTEGHLTMRQGADREESPMTGVCVQQSPVASS Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 458545 | DYRK1A | dual specificity tyrosine phosphorylation regulated kinase 1A | 9598 | VGNC:7682 | OMA, EggNOG |
| Macaque | 693812 | DYRK1A | dual specificity tyrosine phosphorylation regulated kinase 1A | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 13548 | Dyrk1a | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a | 10090 | MGI:1330299 | Inparanoid, OMA, EggNOG |
| Rat | 25255 | Dyrk1a | dual specificity tyrosine phosphorylation regulated kinase 1A | 10116 | RGD:2528 | Inparanoid, OMA, EggNOG |
| Dog | 487755 | DYRK1A | dual specificity tyrosine phosphorylation regulated kinase 1A | 9615 | VGNC:40155 | Inparanoid, OMA, EggNOG |
| Horse | 100051707 | DYRK1A | dual specificity tyrosine phosphorylation regulated kinase 1A | 9796 | VGNC:17376 | Inparanoid, OMA, EggNOG |
| Cow | 532989 | DYRK1A | dual specificity tyrosine phosphorylation regulated kinase 1A | 9913 | VGNC:28279 | Inparanoid, OMA, EggNOG |
| Pig | 100514684 | DYRK1A | dual specificity tyrosine phosphorylation regulated kinase 1A | 9823 | OMA, EggNOG | |
| Opossum | 100019775 | DYRK1A | dual specificity tyrosine phosphorylation regulated kinase 1A | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | 100078677 | DYRK1A | dual specificity tyrosine phosphorylation regulated kinase 1A | 9258 | Inparanoid, OMA, EggNOG | |
| Chicken | 395233 | DYRK1A | dual specificity tyrosine phosphorylation regulated kinase 1A | 9031 | CGNC:11992 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100562279 | dyrk1a | dual specificity tyrosine phosphorylation regulated kinase 1A | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 779733 | dyrk1a | dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 8364 | XB-GENE-1017105 | Inparanoid, OMA, EggNOG |
| Zebrafish | 327466 | dyrk1ab | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b | 7955 | ZDB-GENE-030131-5677 | Inparanoid, OMA, EggNOG |
| Fruitfly | 32771 | mnb | minibrain | 7227 | FBgn0259168 | Inparanoid, EggNOG |
Protein Classes
PANTHER Classes
protein / protein kinase / Dual specificity tyrosine-phosphorylation-regulated kinase 1a
protein / non-receptor serine/threonine protein kinase / Dual specificity tyrosine-phosphorylation-regulated kinase 1a
protein / non-receptor tyrosine protein kinase / Dual specificity tyrosine-phosphorylation-regulated kinase 1a
protein / transferase / Dual specificity tyrosine-phosphorylation-regulated kinase 1a
protein / kinase / Dual specificity tyrosine-phosphorylation-regulated kinase 1a
protein / protein kinase / Dual specificity tyrosine-phosphorylation-regulated kinase 1a
protein / non-receptor serine/threonine protein kinase / Dual specificity tyrosine-phosphorylation-regulated kinase 1a
protein / non-receptor tyrosine protein kinase / Dual specificity tyrosine-phosphorylation-regulated kinase 1a
protein / transferase / Dual specificity tyrosine-phosphorylation-regulated kinase 1a
protein / kinase / Dual specificity tyrosine-phosphorylation-regulated kinase 1a
DTO Classes
protein / Kinase / Protein kinase / CMGC group / DYRK family / Dyrk1 subfamily / Dual specificity tyrosine-phosphorylation-regulated kinase 1a
protein / Kinase / Protein kinase / CMGC group / DYRK family / Dyrk1 subfamily / Dual specificity tyrosine-phosphorylation-regulated kinase 1a
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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