DYRK1A

Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Gene and Protein Information

Gene ID	1859
Uniprot Accession IDs	O60769 Q92582 Q92810 Q9UNM5
Ensembl ID	ENSP00000381932
Symbol	DYRK MNB MNBH MNB DYRK HP86 MNBH MRD7 DYRK1
Family	Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.
Sequence	MHTGGETSACKPSSVRLAPSFSFHAAGLQMAGQMPHSHQYSDRRQPNISDQQVSALSYSDQIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGGHFTAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSSSTTSSSTSSSSTGNQGNQAYQNRPVAANTLDFGQNGAMDVNLTVYSNPRQETGIAGHPTYQFSANTGPAHYMTEGHLTMRQGADREESPMTGVCVQQSPVASS Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	458545	DYRK1A	dual specificity tyrosine phosphorylation regulated kinase 1A	9598	VGNC:7682	OMA, EggNOG
Macaque	693812	DYRK1A	dual specificity tyrosine phosphorylation regulated kinase 1A	9544		Inparanoid, OMA, EggNOG
Mouse	13548	Dyrk1a	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a	10090	MGI:1330299	Inparanoid, OMA, EggNOG
Rat	25255	Dyrk1a	dual specificity tyrosine phosphorylation regulated kinase 1A	10116	RGD:2528	Inparanoid, OMA, EggNOG
Dog	487755	DYRK1A	dual specificity tyrosine phosphorylation regulated kinase 1A	9615	VGNC:40155	Inparanoid, OMA, EggNOG
Horse	100051707	DYRK1A	dual specificity tyrosine phosphorylation regulated kinase 1A	9796	VGNC:17376	Inparanoid, OMA, EggNOG
Cow	532989	DYRK1A	dual specificity tyrosine phosphorylation regulated kinase 1A	9913	VGNC:28279	Inparanoid, OMA, EggNOG
Pig	100514684	DYRK1A	dual specificity tyrosine phosphorylation regulated kinase 1A	9823		OMA, EggNOG
Opossum	100019775	DYRK1A	dual specificity tyrosine phosphorylation regulated kinase 1A	13616		Inparanoid, OMA, EggNOG
Platypus	100078677	DYRK1A	dual specificity tyrosine phosphorylation regulated kinase 1A	9258		Inparanoid, OMA, EggNOG
Chicken	395233	DYRK1A	dual specificity tyrosine phosphorylation regulated kinase 1A	9031	CGNC:11992	Inparanoid, OMA, EggNOG
Anole lizard	100562279	dyrk1a	dual specificity tyrosine phosphorylation regulated kinase 1A	28377		Inparanoid, OMA, EggNOG
Xenopus	779733	dyrk1a	dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	8364	XB-GENE-1017105	Inparanoid, OMA, EggNOG
Zebrafish	327466	dyrk1ab	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b	7955	ZDB-GENE-030131-5677	Inparanoid, OMA, EggNOG
Fruitfly	32771	mnb	minibrain	7227	FBgn0259168	Inparanoid, EggNOG

Protein Classes

PANTHER Classes
protein    /    protein kinase    /    Dual specificity tyrosine-phosphorylation-regulated kinase 1a
protein    /    non-receptor serine/threonine protein kinase    /    Dual specificity tyrosine-phosphorylation-regulated kinase 1a
protein    /    non-receptor tyrosine protein kinase    /    Dual specificity tyrosine-phosphorylation-regulated kinase 1a
protein    /    transferase    /    Dual specificity tyrosine-phosphorylation-regulated kinase 1a
protein    /    kinase    /    Dual specificity tyrosine-phosphorylation-regulated kinase 1a

DTO Classes
protein / Kinase / Protein kinase / CMGC group / DYRK family / Dyrk1 subfamily / Dual specificity tyrosine-phosphorylation-regulated kinase 1a

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

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