CACNA1I

DescriptionVoltage-dependent T-type calcium channel subunit alpha-1I

Gene and Protein Information

Gene ID8911
Uniprot Accession IDs B0QY12 B0QY13 B0QY14 O95504 Q5JZ88 Q7Z6S9 Q8NFX6 Q9NZC8 Q9UH15 Q9UH30 Q9ULU9 Q9UNE6
Ensembl ID ENSP00000385019
Symbol KIAA1120 Cav3.3 ca(v)3.3
FamilyBelongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1I subfamily.
Sequence
MAESASPPSSSAAAPAAEPGVTTEQPGPRSPPSSPPGLEEPLDGADPHVPHPDLAPIAFFCLRQTTSPRNWCIKMVCNPWFECVSMLVILLNCVTLGMYQPCDDMDCLSDRCKILQVFDDFIFIFFAMEMVLKMVALGIFGKKCYLGDTWNRLDFFIVMAGMVEYSLDLQNINLSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCFLEENFTIQGDVALPPYYQPEEDDEMPFICSLSGDNGIMGCHEIPPLKEQGRECCLSKDDVYDFGAGRQDLNASGLCVNWNRYYNVCRTGSANPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQREHRLMLEQRQRYLSSSTVASYAEPGDCYEEIFQYVCHILRKAKRRALGLYQALQSRRQALGPEAPAPAKPGPHAKEPRHYHGKTKGQGDEGRHLGSRHCQTLHGPASPGNDHSGRELCPQHSPLDATPHTLVQPIPATLASDPASCPCCQHEDGRRPSGLGSTDSGQEGSGSGSSAGGEDEADGDGARSSEDGASSELGKEEEEEEQADGAVWLCGDVWRETRAKLRGIVDSKYFNRGIMMAILVNTVSMGIEHHEQPEELTNILEICNVVFTSMFALEMILKLAAFGLFDYLRNPYNIFDSIIVIISIWEIVGQADGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSPWASLYFVALMTFGNYVLFNLLVAILVEGFQAEGDANRSYSDEDQSSSNIEEFDKLQEGLDSSGDPKLCPIPMTPNGHLDPSLPLGGHLGPAGAAGPAPRLSLQPDPMLVALGSRKSSVMSLGRMSYDQRSLSSSRSSYYGPWGRSAAWASRRSSWNSLKHKPPSAEHESLLSAERGGGARVCEVAADEGPPRAAPLHTPHAHHIHHGPHLAHRHRHHRRTLSLDNRDSVDLAELVPAVGAHPRAAWRAAGPAPGHEDCNGRMPSIAKDVFTKMGDRGDRGEDEEEIDYTLCFRVRKMIDVYKPDWCEVREDWSVYLFSPENRFRVLCQTIIAHKLFDYVVLAFIFLNCITIALERPQIEAGSTERIFLTVSNYIFTAIFVGEMTLKVVSLGLYFGEQAYLRSSWNVLDGFLVFVSIIDIVVSLASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYHCLGVDTRNITNRSDCMAANYRWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYNGLDAVAVDQQPVTNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRKAQRLPYYATYCHTRLLIHSMCTSHYLDIFITFIICLNVVTMSLEHYNQPTSLETALKYCNYMFTTVFVLEAVLKLVAFGLRRFFKDRWNQLDLAIVLLSVMGITLEEIEINAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNDENPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRDCTHDERSCLSSLQFVSPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQEDAEMDAELELEMAHGLGPGPRLPTGSPGAPGRGPGGAGGGGDTEGGLCRRCYSPAQENLWLDSVSLIIKDSLEGELTIIDNLSGSIFHHYSSPAGCKKCHHDKQEVQLAETEAFSLNSDRSSSILLGDDLSLEDPTACPPGRKDSKGELDPPEPMRVGDLGECFFPLSSTAVSPDPENFLCEMEEIPFNPVRSWLKHDSSQAPPSPFSPDASSPLLPMPAEFFHPAVSASQKGPEKGTGTGTLPKIALQGSWASLRSPRVNCTLLRQATGSDTSLDASPSSSAGSLQTTLEDSLTLSDSPRRALGPPAPAPGPRAGLSPAARRRLSLRGRGLFSLRGLRAHQRSHSSGGSTSPGCTHHDSMDPSDEEGRGGAGGGGAGSEHSETLSSLSLTSLFCPPPPPPAPGLTPARKFSSTSSLAAPGRPHAAALAHGLARSPSWAADRSKDPPGRAPLPMGLGPLAPPPQPLPGELEPGDAASKRKR
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp458848CACNA1Icalcium voltage-gated channel subunit alpha1 I9598Inparanoid, OMA, EggNOG
Mouse239556Cacna1icalcium channel, voltage-dependent, alpha 1I subunit10090MGI:2178051Inparanoid, OMA, EggNOG
Dog481243CACNA1Icalcium voltage-gated channel subunit alpha1 I9615VGNC:38639Inparanoid, OMA, EggNOG
Horse100070365CACNA1Icalcium voltage-gated channel subunit alpha1 I9796VGNC:49307Inparanoid, OMA, EggNOG
CowCACNA1Icalcium voltage-gated channel subunit alpha1 I [Source:HGNC Symbol;Acc:HGNC:1396]9913OMA, EggNOG
Pig100154640CACNA1Icalcium voltage-gated channel subunit alpha1 I9823OMA, EggNOG
OpossumCACNA1Icalcium voltage-gated channel subunit alpha1 I [Source:HGNC Symbol;Acc:HGNC:1396]13616Inparanoid, OMA, EggNOG
PlatypusCACNA1Icalcium voltage-gated channel subunit alpha1 I [Source:HGNC Symbol;Acc:HGNC:1396]9258OMA, EggNOG
Anole lizard103278866cacna1icalcium voltage-gated channel subunit alpha1 I28377Inparanoid, OMA, EggNOG
Xenopus100494599cacna1icalcium channel, voltage-dependent, T type, alpha 1I subunit8364XB-GENE-983863Inparanoid, OMA
Fruitfly31550Ca-alpha1TCa[2+]-channel protein alpha[[1]] subunit T7227FBgn0264386Inparanoid, EggNOG

Protein Classes

PANTHER Classes
protein    /    transporter    /    calcium channel    /    Voltage-dependent t-type calcium channel subunit alpha-1i
protein    /    transporter    /    voltage-gated sodium channel    /    Voltage-dependent t-type calcium channel subunit alpha-1i
protein    /    transporter    /    voltage-gated calcium channel    /    Voltage-dependent t-type calcium channel subunit alpha-1i
protein    /    transporter    /    sodium channel    /    Voltage-dependent t-type calcium channel subunit alpha-1i
protein    /    transporter    /    voltage-gated ion channel    /    Voltage-dependent t-type calcium channel subunit alpha-1i
DTO Classes
protein    /    Ion channel    /    Calcium channel alpha-1 subunit family    /    CACNA1I subfamily    /    Voltage-dependent t-type calcium channel subunit alpha-1i

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

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