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Protein or Target Summary

Voltage-dependent L-type calcium channel subunit alpha-1C

Gene ID775
uniprotQ13936
Gene NameCACNA1C
Ensernbl IDENSP00000266376
FamilyBelongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1C subfamily.
Sequence
MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRERHVPMCEDLELRRDSGSAGTQAHCLLLRKANPSRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN775CACNA1CVoltage-dependent L-type calcium channel subunit alpha-1CQ13936
MOUSECacna1cVoltage-dependent calcium channelQ0PCR4
MOUSE12288Cacna1cVoltage-dependent L-type calcium channel subunit alphaC7TQ60
MOUSECacna1cVoltage-dependent L-type calcium channel subunit alphaB7ZN95
MOUSE12288Cacna1cVoltage-dependent L-type calcium channel subunit alphaC7TQ61
MOUSECacna1cUncharacterized proteinQ3UY08
MOUSECacna1cVoltage-dependent L-type calcium channel subunit alphaA0A087WPZ8
MOUSECacna1cVoltage-dependent L-type calcium channel subunit alphaA0A087WQJ4
MOUSECacna1cVoltage-dependent L-type calcium channel subunit alphaA0A1W2P731
MOUSECacna1cVoltage-dependent L-type calcium channel subunit alphaA0A087WQT9
MOUSECacna1cVoltage-dependent L-type calcium channel subunit alphaA0A087WS67
MOUSECacna1cVoltage-dependent L-type calcium channel subunit alphaA0A087WR02
MOUSECacna1cVoltage-dependent L-type calcium channel subunit alphaA0A087WRZ6
MOUSE12288Cacna1cVoltage-dependent L-type calcium channel subunit alphaC7TQ58
MOUSE12288Cacna1cVoltage-dependent L-type calcium channel subunit alphaC7TQ62
MOUSECacna1cVoltage-dependent calcium channel splice variant 1.2-bQ0PCR5
MOUSE12288Cacna1cVoltage-dependent L-type calcium channel subunit alphaA0A087WSE7
MOUSE12288Cacna1cVoltage-dependent L-type calcium channel subunit alphaF7C376
MOUSE12288Cacna1cVoltage-dependent L-type calcium channel subunit alphaA0A087WS40
MOUSE12288Cacna1cVoltage-dependent L-type calcium channel subunit alphaF8WJL1
MOUSECacna1cVoltage-dependent L-type calcium channel subunit alphaA0A087WPP1
MOUSECacna1cVoltage-dependent L-type calcium channel subunit alphaA0A1W2P6T3
MOUSECacna1cVoltage-dependent L-type calcium channel subunit alphaA0A1W2P805
MOUSECacna1cVoltage-dependent L-type calcium channel subunit alphaA0A087WRM3
MOUSECacna1cVoltage-dependent L-type calcium channel subunit alphaA0A1W2P6Z7
MOUSECacna1cVoltage-dependent L-type calcium channel subunit alphaQ5S8D1
MOUSE12288Cacna1cVoltage-dependent L-type calcium channel subunit alphaQ0PCR6
MOUSE12288Cacna1cVoltage-dependent L-type calcium channel subunit alphaC7TQ59
MOUSE12288Cacna1cVoltage-dependent L-type calcium channel subunit alphaC7TQ57
MOUSE12288Cacna1cVoltage-dependent L-type calcium channel subunit alpha-1CQ01815
RAT24239Cacna1cVoltage-dependent L-type calcium channel subunit alpha-1CP22002
RATCacna1cVoltage-dependent L-type calcium channel subunit alphaQ8VHT2
RATCacna1cVoltage-dependent L-type calcium channel subunit alphaQ8VHT3
RAT24239Cacna1cVoltage-dependent L-type calcium channel subunit alphaQ71QJ6
RAT24239Cacna1cVoltage-dependent L-type calcium channel subunit alphaA0SLC4
RATCacna1cVoltage-dependent L-type calcium channel subunit alphaA0A0G2QC25
RATCacna1cVoltage-dependent L-type calcium channel subunit alphaF1MA84
RAT24239Cacna1cVoltage-dependent L-type calcium channel subunit alphaA0PJ39
RATCacna1cVoltage-dependent L-type calcium channel subunit alpha-1CE9PT56

Protein Classes

DTO Classes
protein    /    Ion channel    /    Calcium channel alpha-1 subunit family    /    CACNA1C subfamily    /    Voltage-dependent L-type calcium channel subunit alpha-1C

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source
      Source: DataSourcesLicenses.xlsx
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