CAPN1

DescriptionCalpain-1 catalytic subunit

Gene and Protein Information

Gene ID823
Uniprot Accession IDs Q2TTR0 Q6DHV4
Ensembl ID ENSP00000431984
Symbol CANPL1 CANP muCL CANP1 SPG76 CANPL1 muCANP
FamilyBelongs to the peptidase C2 family.
Sequence
MSEEIITPVYCTGVSAQVQKQRARELGLGRHENAIKYLGQDYEQLRVRCLQSGTLFRDEAFPPVPQSLGYKDLGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNDTLLHRVVPHGQSFQNGYAGIFHFQLWQFGEWVDVVVDDLLPIKDGKLVFVHSAEGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILKALERGSLLGCSIDISSVLDMEAITFKKLVKGHAYSVTGAKQVNYRGQVVSLIRMRNPWGEVEWTGAWSDSSSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLEICNLTPDALKSRTIRKWNTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLDETDDPDDYGDRESGCSFVLALMQKHRRRERRFGRDMETIGFAVYEVPPELVGQPAVHLKRDFFLANASRARSEQFINLREVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTVELDDQIQANLPDEQVLSEEEIDENFKALFRQLAGEDMEISVKELRTILNRIISKHKDLRTKGFSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYELIITRYSEPDLAVDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp451317CAPN1calpain 19598VGNC:7514OMA, EggNOG
Macaque716618CAPN1calpain 19544Inparanoid, OMA, EggNOG
Mouse12333Capn1calpain 110090MGI:88263Inparanoid, OMA, EggNOG
Rat29153Capn1calpain 110116RGD:2267Inparanoid, OMA, EggNOG
Dog483745CAPN1calpain 19615VGNC:38698Inparanoid, OMA
Horse100051106CAPN1calpain 19796VGNC:16037Inparanoid, OMA
Cow281661CAPN1calpain 19913VGNC:26740Inparanoid, OMA
Pig397027CAPN1calpain 19823Inparanoid, OMA
Anole lizard100560015capn1calpain 128377Inparanoid, OMA
Xenopus541455capn1calpain 1, (mu/I) large subunit8364XB-GENE-990196Inparanoid, OMA
Zebrafish565825si:dkeyp-50d11.2si:dkeyp-50d11.27955ZDB-GENE-091113-22Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    calcium-binding protein    /    calmodulin    /    Calpain-1 catalytic subunit
protein    /    calcium-binding protein    /    cysteine protease    /    Calpain-1 catalytic subunit
protein    /    calcium-binding protein    /    annexin    /    Calpain-1 catalytic subunit
protein    /    calcium-binding protein    /    protease    /    Calpain-1 catalytic subunit
protein    /    calcium-binding protein    /    hydrolase    /    Calpain-1 catalytic subunit
DTO Classes
protein    /    Enzyme    /    Protease    /    Cysteine protease    /    Calpain-1 catalytic subunit

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source