PRMT5

Description	Protein arginine N-methyltransferase 5

Gene and Protein Information

Gene ID	10419
Uniprot Accession IDs	A8MTP3 A8MZ91 B4DX49 B4DY30 B5BU10 D3DS33 E2QRE7 Q6IBR1 Q9UKH1
Ensembl ID	ENSP00000319169
Symbol	HRMT1L5 IBP72 JBP1 SKB1 HSL7 JBP1 SKB1 IBP72 SKB1Hs HRMT1L5
Family	Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
Sequence	MAAMAVGGAGGSRVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	452789	PRMT5	protein arginine methyltransferase 5	9598	VGNC:3352	OMA, EggNOG
Macaque	712718	PRMT5	protein arginine methyltransferase 5	9544		Inparanoid, OMA, EggNOG
Mouse	27374	Prmt5	protein arginine N-methyltransferase 5	10090	MGI:1351645	Inparanoid, OMA, EggNOG
Rat	364382	Prmt5	protein arginine methyltransferase 5	10116	RGD:1309053	Inparanoid, OMA, EggNOG
Dog	480242	PRMT5	protein arginine methyltransferase 5	9615	VGNC:44998	Inparanoid, OMA, EggNOG
Horse	100052729	PRMT5	protein arginine methyltransferase 5	9796	VGNC:21862	Inparanoid, OMA, EggNOG
Cow	515594	PRMT5	protein arginine methyltransferase 5	9913	VGNC:33350	Inparanoid, OMA, EggNOG
Pig	100294711	PRMT5	protein arginine methyltransferase 5	9823		Inparanoid, OMA, EggNOG
Opossum	100024287	PRMT5	protein arginine methyltransferase 5	13616		Inparanoid, EggNOG
Anole lizard	100555438	prmt5	protein arginine methyltransferase 5	28377		Inparanoid, OMA, EggNOG
Xenopus	100145788	prmt5	protein arginine methyltransferase 5	8364	XB-GENE-975034	Inparanoid, OMA, EggNOG
Zebrafish	368664	prmt5	protein arginine methyltransferase 5	7955	ZDB-GENE-030616-585	Inparanoid, OMA, EggNOG
C. elegans	175717	prmt-5	Protein arginine N-methyltransferase 5	6239		Inparanoid, OMA, EggNOG
Fruitfly	36809	csul	capsuleen	7227	FBgn0015925	Inparanoid, OMA, EggNOG
S.cerevisiae	852431	HSL7	protein arginine N-methyltransferase	4932	S000000337	Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein / signaling molecule / Protein arginine N-methyltransferase 5

DTO Classes
protein / Epigenetic regulator / Writer / Protein methyltransferase / Protein arginine methyltransferase / Protein arginine N-methyltransferase 5

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

🔙[Back to Target (Human)]