Protein or Target Summary

Protein arginine N-methyltransferase 5

Gene ID	10419
uniprot	O14744
Gene Name	PRMT5
Ensernbl ID	ENSP00000319169
Family	Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
Sequence	MAAMAVGGAGGSRVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL Show more

Gene and Protein Information

Species	Gene ID	Gene Symbol	Gene Name	Uniprot
HUMAN	10419	PRMT5	Protein arginine N-methyltransferase 5	O14744
MOUSE		Prmt5	Protein arginine N-methyltransferase 5	F6QQQ6
MOUSE	27374	Prmt5	Protein arginine N-methyltransferase 5	A0A0R4J049
MOUSE		Prmt5	Uncharacterized protein	Q9CRT9
MOUSE		Prmt5	Protein arginine N-methyltransferase 5	A0A2I3BRG2
MOUSE		Prmt5	Protein arginine N-methyltransferase 5	S4R295
MOUSE	27374	Prmt5	Protein arginine N-methyltransferase 5	Q8CIG8
RAT	364382	Prmt5	Protein arginine N-methyltransferase 5	D4A0E8

Protein Classes

PANTHER Classes
protein / signaling molecule / Protein arginine N-methyltransferase 5

DTO Classes
protein / Epigenetic regulator / Writer / Protein methyltransferase / Protein arginine methyltransferase / Protein arginine N-methyltransferase 5

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

Source: TCRDv6_DataSourcesLicenses.xlsx