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BMPR1B

DescriptionBone morphogenetic protein receptor type-1B

Gene and Protein Information

Gene ID658
Uniprot Accession IDs B2R953 B4DSV1 P78366 BMP type-1B receptor
Ensembl ID ENSP00000401907
Symbol ALK6 AMDD BDA2 ALK-6 BDA1D CDw293
FamilyBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Sequence
MLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEEDDSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVDGPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQDETYIPPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTLAKMSESQDIKL
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp461683BMPR1Bbone morphogenetic protein receptor type 1B9598VGNC:7044OMA, EggNOG
Macaque705474BMPR1Bbone morphogenetic protein receptor type 1B9544Inparanoid, OMA, EggNOG
Mouse12167Bmpr1bbone morphogenetic protein receptor, type 1B10090MGI:107191Inparanoid, OMA, EggNOG
Dog478484BMPR1Bbone morphogenetic protein receptor type 1B9615VGNC:38485Inparanoid, OMA
Horse100053554BMPR1Bbone morphogenetic protein receptor type 1B9796VGNC:15852Inparanoid, OMA
Cow407128BMPR1Bbone morphogenetic protein receptor type 1B9913VGNC:26525Inparanoid, OMA
Opossum100016370BMPR1Bbone morphogenetic protein receptor type 1B13616Inparanoid, OMA
Chicken396030BMPR1Bbone morphogenetic protein receptor type 1B9031CGNC:49616Inparanoid, OMA
Anole lizard100553122bmpr1bbone morphogenetic protein receptor type 1B28377Inparanoid, OMA
Xenopus780089bmpr1bbone morphogenetic protein receptor type 1B8364XB-GENE-483455Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    receptor    /    protein kinase receptor    /    Bone morphogenetic protein receptor type-1b
protein    /    receptor    /    TGF-beta receptor    /    Bone morphogenetic protein receptor type-1b
protein    /    receptor    /    serine/threonine protein kinase receptor    /    Bone morphogenetic protein receptor type-1b
protein    /    receptor    /    protein kinase    /    Bone morphogenetic protein receptor type-1b
protein    /    receptor    /    transferase    /    Bone morphogenetic protein receptor type-1b
protein    /    receptor    /    kinase    /    Bone morphogenetic protein receptor type-1b
DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    STKR family    /    STKR Type 1 subfamily    /    Bone morphogenetic protein receptor type-1b

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Bibliography

      1.Aström, A K AK and 7 more authors. 1999-03 Chromosomal localization of three human genes encoding bone morphogenetic protein receptors. [PMID:10051328]
      2.Ebisawa, T T and 7 more authors. 1999-10 Characterization of bone morphogenetic protein-6 signaling pathways in osteoblast differentiation. [PMID:10504300]
      3.Gilboa, L L and 5 more authors. 2000-03 Bone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptors. [PMID:10712517]
      4.Kim, I Y IY and 8 more authors. 2000-06-01 Expression of bone morphogenetic protein receptors type-IA, -IB and -II correlates with tumor grade in human prostate cancer tissues. [PMID:10850425]
      5.Chapman, S C SC and Woodruff, T K TK. 2001-04 Modulation of activin signal transduction by inhibin B and inhibin-binding protein (INhBP). [PMID:11266516]
      6.Parks, W T WT and 12 more authors. 2001-06-01 Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases. [PMID:11279102]
      7.Aoki, H H and 6 more authors. 2001-04 Synergistic effects of different bone morphogenetic protein type I receptors on alkaline phosphatase induction. [PMID:11282024]
      8.Souza, C J CJ and 5 more authors. 2001-05 The Booroola (FecB) phenotype is associated with a mutation in the bone morphogenetic receptor type 1 B (BMPR1B) gene. [PMID:11312159]
      9.Ahmed, N N, Sammons, J J, Carson, R J RJ, Khokher, M A MA and Hassan, H T HT. 2001 Effect of bone morphogenetic protein-6 on haemopoietic stem cells and cytokine production in normal human bone marrow stroma. [PMID:11401330]
      10.Josso, N N, di Clemente, N N and Gouédard, L L. 2001-06-20 Anti-Müllerian hormone and its receptors. [PMID:11420127]