BRAF

DescriptionSerine/threonine-protein kinase B-raf

Gene and Protein Information

Gene ID673
Uniprot Accession IDs A4D1T4 B6HY61 B6HY62 B6HY63 B6HY64 B6HY65 B6HY66 Q13878 Q3MIN6 Q9UDP8 Q9Y6T3
Ensembl ID ENSP00000288602
Symbol BRAF1 RAFB1 NS7 B-raf BRAF1 RAFB1 B-RAF1
FamilyBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
Sequence
MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGAFPVH
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp463781BRAFB-Raf proto-oncogene, serine/threonine kinase9598VGNC:14003OMA, EggNOG
Mouse109880BrafBraf transforming gene10090MGI:88190Inparanoid, OMA, EggNOG
Rat114486BrafB-Raf proto-oncogene, serine/threonine kinase10116RGD:619908Inparanoid, OMA, EggNOG
Dog475526BRAFB-Raf proto-oncogene, serine/threonine kinase9615VGNC:38514Inparanoid, OMA, EggNOG
Horse100065760BRAFB-Raf proto-oncogene, serine/threonine kinase9796VGNC:15875Inparanoid, OMA, EggNOG
Cow536051BRAFB-Raf proto-oncogene, serine/threonine kinase9913VGNC:26551OMA, EggNOG
Pig100514612BRAFB-Raf proto-oncogene, serine/threonine kinase9823OMA, EggNOG
Opossum100024057BRAFB-Raf proto-oncogene, serine/threonine kinase13616Inparanoid, OMA, EggNOG
Chicken396239BRAFB-Raf proto-oncogene, serine/threonine kinase9031CGNC:9744Inparanoid, OMA
Anole lizard100556317brafB-Raf proto-oncogene, serine/threonine kinase28377Inparanoid, OMA
Xenopus779570brafB-Raf proto-oncogene, serine/threonine kinase8364XB-GENE-1014202Inparanoid, OMA
Zebrafish403065brafB-Raf proto-oncogene, serine/threonine kinase7955ZDB-GENE-040805-1Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    RAF family    /    Serine/threonine-protein kinase b-raf

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source