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Protein or Target Summary

Serine/threonine-protein kinase B-raf

Gene ID673
uniprotP15056
Gene NameBRAF
Ensernbl IDENSP00000288602
FamilyBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
Sequence
MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGAFPVH
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN673BRAFSerine/threonine-protein kinase B-rafP15056
MOUSEBrafB-Raf proteinQ9JJU4
MOUSEBrafB-Raf proteinQ9JJU5
MOUSEBrafSerine/threonine-protein kinase B-rafF6SZ47
MOUSEBrafB-Raf proteinQ9JJU6
MOUSE109880BrafSerine/threonine-protein kinase B-rafP28028
RATBrafB-Raf proto-oncogene, serine/threonine kinaseF1M9C3

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    RAF family    /    Serine/threonine-protein kinase b-raf

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source
      Source: DataSourcesLicenses.xlsx
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