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CA14

DescriptionCarbonic anhydrase 14

Gene and Protein Information

Gene ID23632
Uniprot Accession IDs Q5TB24 Q8NCF4
Ensembl ID ENSP00000358107
Symbol CAXiV
FamilyBelongs to the alpha-carbonic anhydrase family.
Sequence
MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLGGLPRKYVAAQLHLHWGQKGSPGGSEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTEEEPSKLLVQNYRALQPLNQRMVFASFIQAGSSYTTGEMLSLGVGILVGCLCLLLAVYFIARKIRKKRLENRKSVVFTSAQATTEA
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp469479CA14carbonic anhydrase 149598VGNC:9849OMA, EggNOG
Macaque706360CA14carbonic anhydrase 149544Inparanoid, OMA, EggNOG
Mouse23831Car14carbonic anhydrase 1410090MGI:1344341Inparanoid, OMA, EggNOG
Rat791259Car14carbonic anhydrase 1410116RGD:1599277Inparanoid, OMA, EggNOG
Dog100855809CA14carbonic anhydrase 149615VGNC:38609Inparanoid, OMA, EggNOG
Horse100054535CA14carbonic anhydrase 149796VGNC:15962Inparanoid, OMA, EggNOG
Cow509027CA14carbonic anhydrase 149913VGNC:26652Inparanoid, OMA, EggNOG
Pig100153371CA14carbonic anhydrase 149823OMA, EggNOG
Opossum100016752CA14carbonic anhydrase 1413616Inparanoid, OMA, EggNOG
Xenopus100126213ca14carbonic anhydrase 148364XB-GENE-855636Inparanoid, OMA, EggNOG
Zebrafish567897ca14carbonic anhydrase XIV7955ZDB-GENE-051030-57Inparanoid, OMA, EggNOG

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details
Recombinant Human Carbonic Anhydrase XIV ProteinHEK293C-10His
Out of Stock
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Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid
      acute quadriplegic myopathy1255Expression AtlasMONDO:0005336
      atypical teratoid / rhabdoid tumor5491Expression AtlasMONDO:0020560
      glioblastoma5998Expression AtlasMONDO:0018177
      group 3 medulloblastoma7142Expression AtlasMONDO:0007959
      medulloblastoma, large-cell6269Expression AtlasMONDO:0002791
      ovarian cancer8576Expression AtlasMONDO:0008170
      primitive neuroectodermal tumor3050Expression AtlasMONDO:0005462
      psoriasis6696Expression AtlasMONDO:0005083
      Atopic dermatitis0JensenLab Experiment TIGA
      Bipolar disorder0JensenLab Experiment TIGA

      Bibliography

      1.Fujikawa-Adachi, K K, Nishimori, I I, Taguchi, T T and Onishi, S S. 1999-10-01 Human carbonic anhydrase XIV (CA14): cDNA cloning, mRNA expression, and mapping to chromosome 1. [PMID:10512682]
      2.Parkkila, S S and 6 more authors. 2001-02-13 Expression of membrane-associated carbonic anhydrase XIV on neurons and axons in mouse and human brain. [PMID:11172051]
      3.Kaunisto, Kari K and 5 more authors. 2002-06 Carbonic anhydrase XIV: luminal expression suggests key role in renal acidification. [PMID:12028451]
      4.Strausberg, Robert L RL and 83 more authors. 2002-12-24 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. [PMID:12477932]
      5.Juel, C C, Lundby, C C, Sander, M M, Calbet, J A L JA and Hall, G van Gv. 2003-04-15 Human skeletal muscle and erythrocyte proteins involved in acid-base homeostasis: adaptations to chronic hypoxia. [PMID:12611920]
      6.Clark, Hilary F HF and 51 more authors. 2003-10 The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. [PMID:12975309]
      7.Tarun, Alice S AS, Bryant, Bruce B, Zhai, Wenwu W, Solomon, Colin C and Shusterman, Dennis D. 2003-09 Gene expression for carbonic anhydrase isoenzymes in human nasal mucosa. [PMID:14578124]
      8.Ota, Toshio T and 156 more authors. 2004-01 Complete sequencing and characterization of 21,243 full-length human cDNAs. [PMID:14702039]
      9.Suzuki, Yutaka Y and 7 more authors. 2004-09 Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. [PMID:15342556]
      10.Gerhard, Daniela S DS and 115 more authors. 2004-10 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). [PMID:15489334]