GRK3

DescriptionBeta-adrenergic receptor kinase 2

Gene and Protein Information

Gene ID157
Uniprot Accession IDs Q9UGW9 Beta-ARK-2
Ensembl ID ENSP00000317578
Symbol ADRBK2 BARK2 BARK2 ADRBK2
FamilyBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
Sequence
MADLEAVLADVSYLMAMEKSKATPAARASKRIVLPEPSIRSVMQKYLAERNEITFDKIFNQKIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLDNEEDRLCRSRQIYDAYIMKELLSCSHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNVELNIHLTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLEHMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPELKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVTETVYEAVNADTDKIEARKRAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNLLTMEQILSVEETQIKDKKCILFRIKGGKQFVLQCESDPEFVQWKKELNETFKEAQRLLRRAPKFLNKPRSGTVELPKPSLCHRNSNGL
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp100614029GRK3G protein-coupled receptor kinase 39598VGNC:12879OMA, EggNOG
Macaque714510GRK3G protein-coupled receptor kinase 39544OMA, EggNOG
Mouse320129Grk3G protein-coupled receptor kinase 310090MGI:87941Inparanoid, OMA, EggNOG
C. elegans175223grk-2G protein-coupled receptor kinase 26239Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    non-receptor serine/threonine protein kinase    /    Beta-adrenergic receptor kinase 2
protein    /    protein kinase    /    Beta-adrenergic receptor kinase 2
protein    /    transferase    /    Beta-adrenergic receptor kinase 2
protein    /    kinase    /    Beta-adrenergic receptor kinase 2
DTO Classes
protein    /    Kinase    /    Protein kinase    /    AGC group    /    GRK family    /    BARK subfamily    /    Beta-adrenergic receptor kinase 2

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source