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Description | Baculoviral IAP repeat-containing protein 3 |
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Gene ID | 330 |
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Uniprot Accession IDs | Q16628 Q9HC27 Q9UP46 |
Ensembl ID | ENSP00000263464 |
Symbol | API2 MIHC RNF49 AIP1 API2 MIHC CIAP2 HAIP1 HIAP1 IAP-1 MALT2 RNF49 c-IAP2 |
Family | Belongs to the IAP family. |
Sequence | MNIVENSIFLSNLMKSANTFELKYDLSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLYPSCRFVQSLNSVNNLEATSQPTFPSSVTNSTHSLLPGTENSGYFRGSYSNSPSNPVNSRANQDFSALMRSSYHCAMNNENARLLTFQTWPLTFLSPTDLAKAGFYYIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIENQLQDTSRYTVSNLSMQTHAARFKTFFNWPSSVLVNPEQLASAGFYYVGNSDDVKCFCCDGGLRCWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESSIIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDLLNAEDEIREEERERATEEKESNDLLLIRKNRMALFQHLTCVIPILDSLLTAGIINEQEHDVIKQKTQTSLQARELIDTILVKGNIAATVFRNSLQEAEAVLYEHLFVQQDIKYIPTEDVSDLPVEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRKCPICRSTIKGTVRTFLS Show more |
Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
---|---|---|---|---|---|---|
Chimp | 451507 | BIRC3 | baculoviral IAP repeat containing 3 | 9598 | VGNC:11266 | OMA, EggNOG |
Mouse | 11796 | Birc3 | baculoviral IAP repeat-containing 3 | 10090 | MGI:1197007 | Inparanoid, OMA, EggNOG |
Rat | 78971 | Birc3 | baculoviral IAP repeat-containing 3 | 10116 | RGD:621282 | Inparanoid, OMA, EggNOG |
Dog | 489433 | BIRC3 | baculoviral IAP repeat containing 3 | 9615 | VGNC:53305 | Inparanoid, OMA |
Horse | 100068894 | BIRC3 | baculoviral IAP repeat containing 3 | 9796 | VGNC:15833 | Inparanoid, OMA |
Cow | 514386 | BIRC3 | baculoviral IAP repeat containing 3 | 9913 | VGNC:26500 | Inparanoid, OMA |
Xenopus | 448041 | birc2 | baculoviral IAP repeat containing 2 | 8364 | XB-GENE-966171 | Inparanoid, OMA |
Zebrafish | 373107 | birc2 | baculoviral IAP repeat containing 2 | 7955 | ZDB-GENE-030825-6 | Inparanoid, OMA |
Fruitfly | 36748 | Diap2 | Death-associated inhibitor of apoptosis 2 | 7227 | FBgn0015247 | Inparanoid, OMA |
Name | Direct Associated Targets | Disease Type | Mondoid |
---|---|---|---|
MALT lymphoma | 486 | Monarch | MONDO:0007650 |
active Crohn's disease | 1059 | Expression Atlas | MONDO:0005011 |
active ulcerative colitis | 2513 | Expression Atlas | MONDO:0005101 |
atopic dermatitis | 916 | Expression Atlas | MONDO:0004980 |
bipolar disorder | 535 | Expression Atlas | MONDO:0004985 |
cutaneous lupus erythematosus | 1094 | Expression Atlas | MONDO:0005282 |
cystic fibrosis | 1831 | Expression Atlas | MONDO:0009061 |
esophageal adenocarcinoma | 754 | Expression Atlas | MONDO:0005028 |
head and neck cancer | 501 | Expression Atlas | MONDO:0005627 |
interstitial cystitis | 2307 | Expression Atlas | MONDO:0018301 |
1.Horrevoets, A J AJ and 5 more authors. 1999-05-15 Vascular endothelial genes that are responsive to tumor necrosis factor-alpha in vitro are expressed in atherosclerotic lesions, including inhibitor of apoptosis protein-1, stannin, and two novel genes. [PMID:10233894] |
2.Suzuki, H H, Motegi, M M, Akagi, T T, Hosokawa, Y Y and Seto, M M. 1999-11-01 API1-MALT1-MLT is involved in mucosa-associated lymphoid tissue lymphoma with t(11;18)(q21;q21) [PMID:10610122] |
3.Yang, Y Y, Fang, S S, Jensen, J P JP, Weissman, A M AM and Ashwell, J D JD. 2000-05-05 Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli. [PMID:10797013] |
4.Verhagen, A M AM and 8 more authors. 2000-07-07 Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. [PMID:10929712] |
5.Baens, M M, Steyls, A A, Dierlamm, J J, De Wolf-Peeters, C C and Marynen, P P. 2000-12 Structure of the MLT gene and molecular characterization of the genomic breakpoint junctions in the t(11;18)(q21;q21) of marginal zone B-cell lymphomas of MALT type. [PMID:11066071] |
6.Werneburg, B G BG, Zoog, S J SJ, Dang, T T TT, Kehry, M R MR and Crute, J J JJ. 2001-11-16 Molecular characterization of CD40 signaling intermediates. [PMID:11562359] |
7.Suzuki, Y Y and 5 more authors. 2001-09 A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death. [PMID:11583623] |
8.Li, Xiaoming X, Yang, Yili Y and Ashwell, Jonathan D JD. 2002-03-21 TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2. [PMID:11907583] |
9.Bertoni, Francesco F, Cavalli, Franco F, Cotter, Finbarr E FE and Zucca, Emanuele E. 2002 Genetic alterations underlying the pathogenesis of MALT lymphoma. [PMID:11960389] |
10.Sharief, M K MK, Noori, M A MA and Zoukos, Y Y. 2002-08 Reduced expression of the inhibitor of apoptosis proteins in T cells from patients with multiple sclerosis following interferon-beta therapy. [PMID:12161039] |