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BACE1
| Description | Beta-secretase 1 |
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Gene and Protein Information
| Gene ID | 23621 |
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| Uniprot Accession IDs | A0M8W7 B0YIU9 E9PE65 H7BXJ9 Q9BYB9 Q9BYC0 Q9BYC1 Q9UJT5 Q9ULS1 |
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| Ensembl ID | ENSP00000318585 |
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| Symbol | BACE KIAA1149 ASP2 BACE HSPC104 |
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| Family | Belongs to the peptidase A1 family. |
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| Sequence | MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 451573 | BACE1 | beta-secretase 1 | 9598 | VGNC:10433 | OMA, EggNOG |
| Macaque | 697694 | BACE1 | beta-secretase 1 | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 23821 | Bace1 | beta-site APP cleaving enzyme 1 | 10090 | MGI:1346542 | Inparanoid, OMA, EggNOG |
| Rat | 29392 | Bace1 | beta-secretase 1 | 10116 | RGD:2191 | Inparanoid, OMA, EggNOG |
| Dog | 489390 | BACE1 | beta-secretase 1 | 9615 | VGNC:38358 | Inparanoid, OMA, EggNOG |
| Horse | 100071137 | BACE1 | beta-secretase 1 | 9796 | VGNC:15750 | OMA, EggNOG |
| Cow | 614333 | BACE1 | beta-secretase 1 | 9913 | VGNC:26400 | Inparanoid, OMA, EggNOG |
| Pig | 100511707 | BACE1 | beta-secretase 1 | 9823 | | Inparanoid, OMA, EggNOG |
| Opossum | 100025518 | BACE1 | beta-secretase 1 | 13616 | | Inparanoid, OMA, EggNOG |
| Platypus | 100079669 | BACE1 | beta-secretase 1 | 9258 | | Inparanoid, OMA, EggNOG |
| Chicken | 419768 | BACE1 | beta-secretase 1 | 9031 | CGNC:5516 | Inparanoid, OMA, EggNOG |
| Xenopus | 779940 | bace1 | beta-site APP-cleaving enzyme 1 | 8364 | XB-GENE-5787150 | Inparanoid, OMA |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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