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BACE2
| Description | Beta-secretase 2 |
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Gene and Protein Information
| Gene ID | 25825 |
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| Uniprot Accession IDs | A8K7P1 Q5DIH8 Q8N2D4 Q9H2V8 Q9NZL1 Q9NZL2 Q9UJT6 |
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| Ensembl ID | ENSP00000332979 |
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| Symbol | AEPLC ALP56 ASP21 ASP1 BAE2 DRAP AEPLC ALP56 ASP21 CDA13 CEAP1 |
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| Family | Belongs to the peptidase A1 family. |
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| Sequence | MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGLALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVIFDRAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMSVCGAILLVLIVLLLLPFRCQRRPRDPEVVNDESSLVRHRWK Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 747819 | BACE2 | beta-site APP-cleaving enzyme 2 | 9598 | | OMA, EggNOG |
| Macaque | 715330 | BACE2 | beta-site APP-cleaving enzyme 2 | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 56175 | Bace2 | beta-site APP-cleaving enzyme 2 | 10090 | MGI:1860440 | Inparanoid, OMA, EggNOG |
| Rat | 288227 | Bace2 | beta-site APP-cleaving enzyme 2 | 10116 | RGD:1303241 | Inparanoid, OMA, EggNOG |
| Dog | 478418 | BACE2 | beta-site APP-cleaving enzyme 2 | 9615 | VGNC:38359 | Inparanoid, OMA, EggNOG |
| Horse | | BACE2 | beta-site APP-cleaving enzyme 2 [Source:HGNC Symbol;Acc:HGNC:934] | 9796 | | OMA, EggNOG |
| Cow | 534774 | BACE2 | beta-site APP-cleaving enzyme 2 | 9913 | VGNC:26401 | Inparanoid, OMA, EggNOG |
| Pig | 100517374 | BACE2 | beta-site APP-cleaving enzyme 2 | 9823 | | OMA, EggNOG |
| Opossum | 100016587 | BACE2 | beta-site APP-cleaving enzyme 2 | 13616 | | Inparanoid, OMA, EggNOG |
| Platypus | | BACE2 | beta-site APP-cleaving enzyme 2 [Source:HGNC Symbol;Acc:HGNC:934] | 9258 | | OMA, EggNOG |
| Anole lizard | 100552914 | bace2 | beta-site APP-cleaving enzyme 2 | 28377 | | Inparanoid, OMA |
| Xenopus | 100216145 | bace2 | beta-site APP-cleaving enzyme 2 | 8364 | XB-GENE-1014090 | Inparanoid, OMA |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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