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ACVR2A

DescriptionActivin receptor type-2A

Gene and Protein Information

Gene ID92
Uniprot Accession IDs B2RAB8 B4DWQ2 D3DP85 Q53TH4 Q6NWV2 Q92474
Ensembl ID ENSP00000241416
Symbol ACVR2 ACVR2 ACTRII
FamilyBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Sequence
MGAAAKLAFAVFLISCSSGAILGRSETQECLFFNANWEKDRTNQTGVEPCYGDKDKRRHCFATWKNISGSIEIVKQGCWLDDINCYDRTDCVEKKDSPEVYFCCCEGNMCNEKFSYFPEMEVTQPTSNPVTPKPPYYNILLYSLVPLMLIAGIVICAFWVYRHHKMAYPPVLVPTQDPGPPPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCVGERITQMQRLTNIITTEDIVTVVTMVTNVDFPPKESSL
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp459646ACVR2Aactivin A receptor type 2A9598VGNC:10526OMA, EggNOG
Macaque707017ACVR2Aactivin A receptor type 2A9544Inparanoid, OMA, EggNOG
Mouse11480Acvr2aactivin receptor IIA10090MGI:102806Inparanoid, OMA, EggNOG
Rat29263Acvr2aactivin A receptor type 2A10116RGD:70911Inparanoid, OMA, EggNOG
Dog476140ACVR2Aactivin A receptor type 2A9615VGNC:37564Inparanoid, OMA
Horse100049823ACVR2Aactivin A receptor type 2A9796VGNC:15038Inparanoid, OMA
Cow281598ACVR2Aactivin A receptor type 2A9913VGNC:25595Inparanoid, OMA
Opossum100018756ACVR2Aactivin A receptor type 2A13616Inparanoid, OMA
Chicken396324ACVR2Aactivin A receptor type 2A9031CGNC:9451Inparanoid, OMA
Anole lizard100562173acvr2aactivin A receptor type 2A28377Inparanoid, OMA
Xenopus100216172acvr2aactivin A receptor type 2A8364XB-GENE-484012Inparanoid, OMA
Zebrafish553359acvr2aaactivin A receptor type 2Aa7955ZDB-GENE-980526-227Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    receptor    /    protein kinase receptor    /    Activin receptor type-2a
protein    /    receptor    /    TGF-beta receptor    /    Activin receptor type-2a
protein    /    receptor    /    serine/threonine protein kinase receptor    /    Activin receptor type-2a
protein    /    receptor    /    protein kinase    /    Activin receptor type-2a
protein    /    receptor    /    transferase    /    Activin receptor type-2a
protein    /    receptor    /    kinase    /    Activin receptor type-2a
DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    STKR family    /    STKR Type 2 subfamily    /    Activin receptor type-2a

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source
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