ACVR2A

DescriptionActivin receptor type-2A

Gene and Protein Information

Gene ID92
Uniprot Accession IDs B2RAB8 B4DWQ2 D3DP85 Q53TH4 Q6NWV2 Q92474
Ensembl ID ENSP00000241416
Symbol ACVR2 ACVR2 ACTRII
FamilyBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Sequence
MGAAAKLAFAVFLISCSSGAILGRSETQECLFFNANWEKDRTNQTGVEPCYGDKDKRRHCFATWKNISGSIEIVKQGCWLDDINCYDRTDCVEKKDSPEVYFCCCEGNMCNEKFSYFPEMEVTQPTSNPVTPKPPYYNILLYSLVPLMLIAGIVICAFWVYRHHKMAYPPVLVPTQDPGPPPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCVGERITQMQRLTNIITTEDIVTVVTMVTNVDFPPKESSL
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp459646ACVR2Aactivin A receptor type 2A9598VGNC:10526OMA, EggNOG
Macaque707017ACVR2Aactivin A receptor type 2A9544Inparanoid, OMA, EggNOG
Mouse11480Acvr2aactivin receptor IIA10090MGI:102806Inparanoid, OMA, EggNOG
Rat29263Acvr2aactivin A receptor type 2A10116RGD:70911Inparanoid, OMA, EggNOG
Dog476140ACVR2Aactivin A receptor type 2A9615VGNC:37564Inparanoid, OMA
Horse100049823ACVR2Aactivin A receptor type 2A9796VGNC:15038Inparanoid, OMA
Cow281598ACVR2Aactivin A receptor type 2A9913VGNC:25595Inparanoid, OMA
Opossum100018756ACVR2Aactivin A receptor type 2A13616Inparanoid, OMA
Chicken396324ACVR2Aactivin A receptor type 2A9031CGNC:9451Inparanoid, OMA
Anole lizard100562173acvr2aactivin A receptor type 2A28377Inparanoid, OMA
Xenopus100216172acvr2aactivin A receptor type 2A8364XB-GENE-484012Inparanoid, OMA
Zebrafish553359acvr2aaactivin A receptor type 2Aa7955ZDB-GENE-980526-227Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    receptor    /    protein kinase receptor    /    Activin receptor type-2a
protein    /    receptor    /    TGF-beta receptor    /    Activin receptor type-2a
protein    /    receptor    /    serine/threonine protein kinase receptor    /    Activin receptor type-2a
protein    /    receptor    /    protein kinase    /    Activin receptor type-2a
protein    /    receptor    /    transferase    /    Activin receptor type-2a
protein    /    receptor    /    kinase    /    Activin receptor type-2a
DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    STKR family    /    STKR Type 2 subfamily    /    Activin receptor type-2a

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

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