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Protein or Target Summary

A disintegrin and metalloproteinase with thrombospondin motifs 5

Gene ID11096
uniprotQ9UNA0
Gene NameADAMTS5
Ensernbl IDENSP00000284987
Sequence
MLLGWASLLLCAFRLPLAAVGPAATPAQDKAGQPPTAAAAAQPRRRQGEEVQERAEPPGHPHPLAQRRRSKGLVQNIDQLYSGGGKVGYLVYAGGRRFLLDLERDGSVGIAGFVPAGGGTSAPWRHRSHCFYRGTVDGSPRSLAVFDLCGGLDGFFAVKHARYTLKPLLRGPWAEEEKGRVYGDGSARILHVYTREGFSFEALPPRASCETPASTPEAHEHAPAHSNPSGRAALASQLLDQSALSPAGGSGPQTWWRRRRRSISRARQVELLLVADASMARLYGRGLQHYLLTLASIANRLYSHASIENHIRLAVVKVVVLGDKDKSLEVSKNAATTLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSCDTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGHLLGLSHDDSKFCEETFGSTEDKRLMSSILTSIDASKPWSKCTSATITEFLDDGHGNCLLDLPRKQILGPEELPGQTYDATQQCNLTFGPEYSVCPGMDVCARLWCAVVRQGQMVCLTKKLPAVEGTPCGKGRICLQGKCVDKTKKKYYSTSSHGNWGSWGSWGQCSRSCGGGVQFAYRHCNNPAPRNNGRYCTGKRAIYRSCSLMPCPPNGKSFRHEQCEAKNGYQSDAKGVKTFVEWVPKYAGVLPADVCKLTCRAKGTGYYVVFSPKVTDGTECRLYSNSVCVRGKCVRTGCDGIIGSKLQYDKCGVCGGDNSSCTKIVGTFNKKSKGYTDVVRIPEGATHIKVRQFKAKDQTRFTAYLALKKKNGEYLINGKYMISTSETIIDINGTVMNYSGWSHRDDFLHGMGYSATKEILIVQILATDPTKPLDVRYSFFVPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGWHTRTVQCQDGNRKLAKGCPLSQRPSAFKQCLLKKC
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN11096ADAMTS5A disintegrin and metalloproteinase with thrombospondin motifs 5Q9UNA0
MOUSE23794Adamts5Uncharacterized proteinQ8BGP4
MOUSE23794Adamts5A disintegrin and metalloproteinase with thrombospondin motifs 5Q9R001
RAT304135Adamts5ADAMTS5Q6TY19
RATAdamts5A disintegrin-like and metallopeptidase (Reprolysin type) with thrombospondin type 1 motif, 5 (Aggrecanase-2)G3V673

Protein Classes

PANTHER Classes
protein    /    extracellular matrix protein    /    protease    /    A disintegrin and metalloproteinase with thrombospondin motifs 5
protein    /    extracellular matrix protein    /    serine protease inhibitor    /    A disintegrin and metalloproteinase with thrombospondin motifs 5
protein    /    extracellular matrix protein    /    hydrolase    /    A disintegrin and metalloproteinase with thrombospondin motifs 5
protein    /    extracellular matrix protein    /    extracellular matrix glycoprotein    /    A disintegrin and metalloproteinase with thrombospondin motifs 5
protein    /    extracellular matrix protein    /    metalloprotease    /    A disintegrin and metalloproteinase with thrombospondin motifs 5
DTO Classes
protein    /    Enzyme    /    Protease    /    Metalloprotease    /    A disintegrin and metalloproteinase with thrombospondin motifs 5

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source