ADAMTS5

DescriptionA disintegrin and metalloproteinase with thrombospondin motifs 5

Gene and Protein Information

Gene ID11096
Uniprot Accession IDs Q52LV4 Q9UKP2 ADAM-TS 5
Ensembl ID ENSP00000284987
Symbol ADAMTS11 ADMP2 ADMP-2 ADAM-TS5 ADAMTS-5 ADAMTS11 ADAM-TS 5 ADAMTS-11 ADAM-TS 11
Sequence
MLLGWASLLLCAFRLPLAAVGPAATPAQDKAGQPPTAAAAAQPRRRQGEEVQERAEPPGHPHPLAQRRRSKGLVQNIDQLYSGGGKVGYLVYAGGRRFLLDLERDGSVGIAGFVPAGGGTSAPWRHRSHCFYRGTVDGSPRSLAVFDLCGGLDGFFAVKHARYTLKPLLRGPWAEEEKGRVYGDGSARILHVYTREGFSFEALPPRASCETPASTPEAHEHAPAHSNPSGRAALASQLLDQSALSPAGGSGPQTWWRRRRRSISRARQVELLLVADASMARLYGRGLQHYLLTLASIANRLYSHASIENHIRLAVVKVVVLGDKDKSLEVSKNAATTLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSCDTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGHLLGLSHDDSKFCEETFGSTEDKRLMSSILTSIDASKPWSKCTSATITEFLDDGHGNCLLDLPRKQILGPEELPGQTYDATQQCNLTFGPEYSVCPGMDVCARLWCAVVRQGQMVCLTKKLPAVEGTPCGKGRICLQGKCVDKTKKKYYSTSSHGNWGSWGSWGQCSRSCGGGVQFAYRHCNNPAPRNNGRYCTGKRAIYRSCSLMPCPPNGKSFRHEQCEAKNGYQSDAKGVKTFVEWVPKYAGVLPADVCKLTCRAKGTGYYVVFSPKVTDGTECRLYSNSVCVRGKCVRTGCDGIIGSKLQYDKCGVCGGDNSSCTKIVGTFNKKSKGYTDVVRIPEGATHIKVRQFKAKDQTRFTAYLALKKKNGEYLINGKYMISTSETIIDINGTVMNYSGWSHRDDFLHGMGYSATKEILIVQILATDPTKPLDVRYSFFVPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGWHTRTVQCQDGNRKLAKGCPLSQRPSAFKQCLLKKC
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp473935ADAMTS5ADAM metallopeptidase with thrombospondin type 1 motif 59598VGNC:3744OMA, EggNOG
Macaque707672ADAMTS5ADAM metallopeptidase with thrombospondin type 1 motif 59544Inparanoid, OMA
Mouse23794Adamts5a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)10090MGI:1346321Inparanoid, OMA
Rat304135Adamts5ADAM metallopeptidase with thrombospondin type 1 motif, 510116RGD:735196Inparanoid, OMA
Dog487713ADAMTS5ADAM metallopeptidase with thrombospondin type 1 motif 59615VGNC:37601Inparanoid, OMA
Cow286805ADAMTS5ADAM metallopeptidase with thrombospondin type 1 motif 59913VGNC:50085OMA, EggNOG
Opossum100021415ADAMTS5ADAM metallopeptidase with thrombospondin type 1 motif 513616Inparanoid, OMA, EggNOG
Chicken427971ADAMTS5ADAM metallopeptidase with thrombospondin type 1 motif 59031CGNC:11783Inparanoid, OMA, EggNOG
Anole lizard100552915adamts5ADAM metallopeptidase with thrombospondin type 1 motif 528377Inparanoid, OMA
Xenopusadamts5ADAM metallopeptidase with thrombospondin type 1 motif 5 [Source:Xenbase;Acc:XB-GENE-961098]8364OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    extracellular matrix protein    /    protease    /    A disintegrin and metalloproteinase with thrombospondin motifs 5
protein    /    extracellular matrix protein    /    serine protease inhibitor    /    A disintegrin and metalloproteinase with thrombospondin motifs 5
protein    /    extracellular matrix protein    /    hydrolase    /    A disintegrin and metalloproteinase with thrombospondin motifs 5
protein    /    extracellular matrix protein    /    extracellular matrix glycoprotein    /    A disintegrin and metalloproteinase with thrombospondin motifs 5
protein    /    extracellular matrix protein    /    metalloprotease    /    A disintegrin and metalloproteinase with thrombospondin motifs 5
DTO Classes
protein    /    Enzyme    /    Protease    /    Metalloprotease    /    A disintegrin and metalloproteinase with thrombospondin motifs 5

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source