ACVR2B

DescriptionActivin receptor type-2B

Gene and Protein Information

Gene ID93
Uniprot Accession IDs Q4VAV0
Ensembl ID ENSP00000340361
Symbol HTX4 ACTRIIB ActR-IIB
FamilyBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Sequence
MTAPWVALALLWGSLCAGSGRGEAETRECIYYNANWELERTNQSGLERCEGEQDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp460271ACVR2Bactivin A receptor type 2B9598VGNC:11330OMA, EggNOG
Macaque696071ACVR2Bactivin A receptor type 2B9544Inparanoid, OMA, EggNOG
Mouse11481Acvr2bactivin receptor IIB10090MGI:87912Inparanoid, OMA, EggNOG
Rat25366Acvr2bactivin A receptor type 2B10116RGD:2028Inparanoid, OMA, EggNOG
Dog485590ACVR2Bactivin A receptor type 2B9615VGNC:37565Inparanoid, OMA, EggNOG
Horse100053588ACVR2Bactivin A receptor type 2B9796VGNC:15039Inparanoid, OMA
Cow282131ACVR2Bactivin A receptor type 2B9913VGNC:25596Inparanoid, OMA, EggNOG
Pig448845ACVR2Bactivin A receptor type 2B9823Inparanoid, OMA
Opossum100029516ACVR2Bactivin A receptor type 2B13616Inparanoid, OMA, EggNOG
Chicken374213ACVR2Bactivin A receptor type 2B9031CGNC:4620Inparanoid, OMA
Anole lizard100565604acvr2bactivin A receptor type 2B28377Inparanoid, OMA, EggNOG
Xenopus448641acvr2bactivin A receptor type 2B8364XB-GENE-484248Inparanoid, OMA
Fruitfly41772putpunt7227FBgn0003169Inparanoid, EggNOG

Protein Classes

PANTHER Classes
protein    /    receptor    /    protein kinase receptor    /    Activin receptor type-2b
protein    /    receptor    /    TGF-beta receptor    /    Activin receptor type-2b
protein    /    receptor    /    serine/threonine protein kinase receptor    /    Activin receptor type-2b
protein    /    receptor    /    protein kinase    /    Activin receptor type-2b
protein    /    receptor    /    transferase    /    Activin receptor type-2b
protein    /    receptor    /    kinase    /    Activin receptor type-2b
DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    STKR family    /    STKR Type 2 subfamily    /    Activin receptor type-2b

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

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