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Protein or Target Summary

Activin receptor type-2B

Gene ID93
uniprotQ13705
Gene NameACVR2B
Ensernbl IDENSP00000340361
FamilyBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Sequence
MTAPWVALALLWGSLCAGSGRGEAETRECIYYNANWELERTNQSGLERCEGEQDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN93ACVR2BActivin receptor type-2BQ13705
MOUSE11481Acvr2bActivin receptor type-2BP27040
RAT25366Acvr2bSerine/threonine-protein kinase receptorA0A0G2JSN4
RAT25366Acvr2bActivin receptor type-2BP38445

Protein Classes

PANTHER Classes
protein    /    receptor    /    protein kinase receptor    /    Activin receptor type-2b
protein    /    receptor    /    TGF-beta receptor    /    Activin receptor type-2b
protein    /    receptor    /    serine/threonine protein kinase receptor    /    Activin receptor type-2b
protein    /    receptor    /    protein kinase    /    Activin receptor type-2b
protein    /    receptor    /    transferase    /    Activin receptor type-2b
protein    /    receptor    /    kinase    /    Activin receptor type-2b
DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    STKR family    /    STKR Type 2 subfamily    /    Activin receptor type-2b

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

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