AURKB

DescriptionAurora kinase B

Gene and Protein Information

Gene ID9212
Uniprot Accession IDs B4DNM4 C7G533 C7G534 C7G535 D3DTR4 J9JID1 O14630 O60446 O95083 Q96DV5 Q9UQ46
Ensembl ID ENSP00000313950
Symbol AIK2 AIM1 AIRK2 ARK2 STK1 STK12 STK5 AIK2 AIM1 ARK2 AurB IPL1 STK5 AIM-1 ARK-2 STK-1 STK12 PPP1R48 aurkb-sv1 aurkb-sv2
FamilyBelongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
Sequence
MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp107969261AURKBaurora kinase B9598VGNC:9128OMA, EggNOG
Macaque721955AURKBaurora kinase B9544Inparanoid, OMA, EggNOG
Mouse20877Aurkbaurora kinase B10090MGI:107168Inparanoid, OMA, EggNOG
Rat114592Aurkbaurora kinase B10116RGD:621625Inparanoid, OMA, EggNOG
Dog479492AURKBaurora kinase B9615VGNC:38312Inparanoid, OMA, EggNOG
Horse100073050AURKBaurora kinase B9796VGNC:15704Inparanoid, OMA, EggNOG
Cow360192AURKBaurora kinase B9913VGNC:26351Inparanoid, OMA
Pig396955AURKBaurora kinase B9823Inparanoid, OMA, EggNOG
Anole lizard100557050LOC100557050aurora kinase C28377OMA, EggNOG
Xenopus549613aurkbaurora kinase B8364XB-GENE-1019626Inparanoid, OMA
C. elegans172268air-2Aurora/IPL1-related protein kinase 26239OMA, EggNOG
S.cerevisiae855892IPL1aurora kinase4932S000006130OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    non-receptor serine/threonine protein kinase    /    Aurora kinase b
protein    /    protein kinase    /    Aurora kinase b
protein    /    transferase    /    Aurora kinase b
protein    /    kinase    /    Aurora kinase b
DTO Classes
protein    /    Kinase    /    Protein kinase    /    Other group    /    AUR family    /    Aurora kinase b

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source