CDK6

DescriptionCyclin-dependent kinase 6

Gene and Protein Information

Gene ID1021
Uniprot Accession IDs A4D1G0
Ensembl ID ENSP00000265734
Symbol CDKN6 MCPH12 PLSTIRE
FamilyBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Sequence
MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSELNTA
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp746968CDK6cyclin dependent kinase 69598VGNC:13637OMA, EggNOG
Macaque701822CDK6cyclin dependent kinase 69544Inparanoid, OMA, EggNOG
Mouse12571Cdk6cyclin-dependent kinase 610090MGI:1277162Inparanoid, OMA, EggNOG
Rat114483Cdk6cyclin-dependent kinase 610116RGD:621121Inparanoid, OMA, EggNOG
Dog609920CDK6cyclin dependent kinase 69615VGNC:54756Inparanoid, OMA
Horse100061625CDK6cyclin dependent kinase 69796VGNC:16354Inparanoid, OMA
Cow511754CDK6cyclin dependent kinase 69913VGNC:27133Inparanoid, OMA
Opossum100021675CDK6cyclin dependent kinase 613616Inparanoid, OMA, EggNOG
Chicken420558CDK6cyclin dependent kinase 69031CGNC:51286Inparanoid, OMA, EggNOG
Anole lizard100558412cdk6cyclin dependent kinase 628377Inparanoid, OMA
Xenopuscdk6cyclin-dependent kinase 6 [Source:Xenbase;Acc:XB-GENE-985427]8364OMA, EggNOG
Zebrafish100034507cdk6cyclin-dependent kinase 67955ZDB-GENE-060503-786Inparanoid, OMA
C. elegans181472cdk-4Cyclin-dependent kinase 4 homolog6239OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    non-receptor serine/threonine protein kinase    /    Cyclin-dependent kinase 6
protein    /    protein kinase    /    Cyclin-dependent kinase 6
protein    /    non-receptor tyrosine protein kinase    /    Cyclin-dependent kinase 6
protein    /    transferase    /    Cyclin-dependent kinase 6
protein    /    kinase    /    Cyclin-dependent kinase 6
DTO Classes
protein    /    Kinase    /    Protein kinase    /    CMGC group    /    CDK family    /    CDK4 subfamily    /    Cyclin-dependent kinase 6

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source