POLD1

DescriptionDNA polymerase delta catalytic subunit

Gene and Protein Information

Gene ID5424
Uniprot Accession IDs Q8NER3 Q96H98
Ensembl ID ENSP00000406046
Symbol POLD CDC2 MDPL POLD CRCS10
FamilyBelongs to the DNA polymerase type-B family.
Sequence
MDGKRRPGPGPGVPPKRARGGLWDDDDAPRPSQFEEDLALMEEMEAEHRLQEQEEEELQSVLEGVADGQVPPSAIDPRWLRPTPPALDPQTEPLIFQQLEIDHYVGPAQPVPGGPPPSRGSVPVLRAFGVTDEGFSVCCHIHGFAPYFYTPAPPGFGPEHMGDLQRELNLAISRDSRGGRELTGPAVLAVELCSRESMFGYHGHGPSPFLRITVALPRLVAPARRLLEQGIRVAGLGTPSFAPYEANVDFEIRFMVDTDIVGCNWLELPAGKYALRLKEKATQCQLEADVLWSDVVSHPPEGPWQRIAPLRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRWGEPEPFLRLALTLRPCAPILGAKVQSYEKEEDLLQAWSTFIRIMDPDVITGYNIQNFDLPYLISRAQTLKVQTFPFLGRVAGLCSNIRDSSFQSKQTGRRDTKVVSMVGRVQMDMLQVLLREYKLRSYTLNAVSFHFLGEQKEDVQHSIITDLQNGNDQTRRRLAVYCLKDAYLPLRLLERLMVLVNAVEMARVTGVPLSYLLSRGQQVKVVSQLLRQAMHEGLLMPVVKSEGGEDYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPGTAQKLGLTEDQFIRTPTGDEFVKTSVRKGLLPQILENLLSARKRAKAELAKETDPLRRQVLDGRQLALKVSANSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVESKYTVENGYSTSAKVVYGDTDSVMCRFGVSSVAEAMALGREAADWVSGHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRPDAHDRMDCKGLEAVRRDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVISDLLCNRIDISQLVITKELTRAASDYAGKQAHVELAERMRKRDPGSAPSLGDRVPYVIISAAKGVAAYMKSEDPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILGEGRAEAVLLRGDHTRCKTVLTGKVGGLLAFAKRRNCCIGCRTVLSHQGAVCEFCQPRESELYQKEVSHLNALEERFSRLWTQCQRCQGSLHEDVICTSRDCPIFYMRKKVRKDLEDQEQLLRRFGPPGPEAW
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Macaque719262LOC719262transcription factor Spi-B9544OMA, EggNOG
Mouse18971Pold1polymerase (DNA directed), delta 1, catalytic subunit10090MGI:97741Inparanoid, OMA, EggNOG
Rat59294Pold1DNA polymerase delta 1, catalytic subunit10116RGD:621839Inparanoid, OMA, EggNOG
Dog610047POLD1DNA polymerase delta 1, catalytic subunit9615VGNC:44774Inparanoid, OMA, EggNOG
Horse100052455POLD1DNA polymerase delta 1, catalytic subunit9796VGNC:21651Inparanoid, OMA, EggNOG
Cow281990POLD1DNA polymerase delta 1, catalytic subunit9913VGNC:33113Inparanoid, OMA, EggNOG
Pig100525752POLD1DNA polymerase delta 1, catalytic subunit9823Inparanoid, OMA, EggNOG
Anole lizard100564729pold1DNA polymerase delta 1, catalytic subunit28377Inparanoid, OMA, EggNOG
Xenopus734063pold1polymerase (DNA directed), delta 1, catalytic subunit8364XB-GENE-1002131Inparanoid, OMA, EggNOG
Zebrafish556456pold1polymerase (DNA directed), delta 1, catalytic subunit7955ZDB-GENE-060429-1Inparanoid, OMA, EggNOG
C. elegans179652F10C2.4DNA polymerase delta catalytic subunit6239Inparanoid, OMA
Fruitfly39746DNApol-deltaDNA-polymerase-delta7227FBgn0263600Inparanoid, OMA
S.cerevisiae851456POL3DNA-directed DNA polymerase delta POL34932S000002260Inparanoid, OMA

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source