DPYD
| Description | Dihydropyrimidine dehydrogenase [NADP(+)] |
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Gene and Protein Information
| Gene ID | 1806 |
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| Uniprot Accession IDs | A2RRQ2 A2RRQ3 A8K5A2 A8MWG9 B1AN21 E9PFN1 Q16694 Q16761 Q32NB0 Q96HL6 Q96TH1 DHPDHase |
| Ensembl ID | ENSP00000359211 |
| Symbol | DHP DPD DHPDHASE |
| Family | Belongs to the dihydropyrimidine dehydrogenase family. |
| Sequence | MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMIFSDNPLGLTCGMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATEVFKAMSIPQIRNPSLPPPEKMSEAYSAKIALFGAGPASISCASFLARLGYSDITIFEKQEYVGGLSTSEIPQFRLPYDVVNFEIELMKDLGVKIICGKSLSVNEMTLSTLKEKGYKAAFIGIGLPEPNKDAIFQGLTQDQGFYTSKDFLPLVAKGSKAGMCACHSPLPSIRGVVIVLGAGDTAFDCATSALRCGARRVFIVFRKGFVNIRAVPEEMELAKEEKCEFLPFLSPRKVIVKGGRIVAMQFVRTEQDETGKWNEDEDQMVHLKADVVISAFGSVLSDPKVKEALSPIKFNRWGLPEVDPETMQTSEAWVFAGGDVVGLANTTVESVNDGKQASWYIHKYVQSQYGASVSAKPELPLFYTPIDLVDISVEMAGLKFINPFGLASATPATSTSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIRGTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGANGVTATNTVSGLMGLKSDGTPWPAVGIAKRTTYGGVSGTAIRPIALRAVTSIARALPGFPILATGGIDSAESGLQFLHSGASVLQVCSAIQNQDFTVIEDYCTGLKALLYLKSIEELQDWDGQSPATVSHQKGKPVPRIAELMDKKLPSFGPYLEQRKKIIAENKIRLKEQNVAFSPLKRNCFIPKRPIPTIKDVIGKALQYLGTFGELSNVEQVVAMIDEEMCINCGKCYMTCNDSGYQAIQFDPETHLPTITDTCTGCTLCLSVCPIVDCIKMVSRTTPYEPKRGVPLSVNPVC Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 457047 | DPYD | dihydropyrimidine dehydrogenase | 9598 | VGNC:10605 | OMA, EggNOG |
| Macaque | 715672 | DPYD | dihydropyrimidine dehydrogenase | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 99586 | Dpyd | dihydropyrimidine dehydrogenase | 10090 | MGI:2139667 | Inparanoid, OMA, EggNOG |
| Dog | 479935 | DPYD | dihydropyrimidine dehydrogenase | 9615 | VGNC:40081 | Inparanoid, OMA, EggNOG |
| Horse | 100057177 | DPYD | dihydropyrimidine dehydrogenase | 9796 | VGNC:17302 | Inparanoid, OMA, EggNOG |
| Cow | 281124 | DPYD | dihydropyrimidine dehydrogenase | 9913 | VGNC:28193 | Inparanoid, OMA, EggNOG |
| Pig | 397109 | DPYD | dihydropyrimidine dehydrogenase | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100032923 | DPYD | dihydropyrimidine dehydrogenase | 13616 | Inparanoid, OMA, EggNOG | |
| Chicken | 429083 | DPYD | dihydropyrimidine dehydrogenase | 9031 | CGNC:4104 | Inparanoid, OMA |
| Zebrafish | 405829 | dpydb | dihydropyrimidine dehydrogenase b | 7955 | ZDB-GENE-040426-2459 | OMA, EggNOG |
| C. elegans | 180818 | dpyd-1 | Dihydropyrimidine dehydrogenase [NADP(+)] | 6239 | Inparanoid, OMA, EggNOG |
Protein Classes
PANTHER Classes
protein / oxidoreductase / dehydrogenase / Dihydropyrimidine dehydrogenase [NADP(+)]
protein / oxidoreductase / reductase / Dihydropyrimidine dehydrogenase [NADP(+)]
protein / oxidoreductase / dehydrogenase / Dihydropyrimidine dehydrogenase [NADP(+)]
protein / oxidoreductase / reductase / Dihydropyrimidine dehydrogenase [NADP(+)]
DTO Classes
protein / Enzyme / Oxidoreductase / Dehydrogenase / Dihydropyrimidine dehydrogenase [NADP(+)]
protein / Enzyme / Oxidoreductase / Dehydrogenase / Dihydropyrimidine dehydrogenase [NADP(+)]
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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