COMT

DescriptionCatechol O-methyltransferase

Gene and Protein Information

Gene ID1312
Uniprot Accession IDs A8MPV9 Q6IB07 Q6ICE6 Q9BWC7
Ensembl ID ENSP00000354511
Symbol HEL-S-98n
FamilyBelongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
Sequence
MPEAPPLLLAAVLLGLVLLVVLLLLLRHWGWGLCLIGWNEFILQPIHNLLMGDTKEQRILNHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGVKDKVTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFECTHYQSFLEYREVVDGLEKAIYKGPGSEAGP
Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp458655COMTcatechol-O-methyltransferase9598VGNC:12831OMA, EggNOG
Mouse12846Comtcatechol-O-methyltransferase10090MGI:88470Inparanoid, OMA, EggNOG
Rat24267Comtcatechol-O-methyltransferase10116RGD:2379Inparanoid, OMA, EggNOG
Dog445450COMTcatechol-O-methyltransferase9615VGNC:39501Inparanoid, OMA, EggNOG
Pig100155530COMTcatechol-O-methyltransferase9823Inparanoid, OMA, EggNOG
Chicken416783MIR4761microRNA 47619031CGNC:1439OMA, EggNOG
Xenopus100135405LOC100135405uncharacterized LOC1001354058364Inparanoid, OMA
Xenopus549111comtcatechol-O-methyltransferase8364XB-GENE-948947OMA, EggNOG
Zebrafish561372comtacatechol-O-methyltransferase a7955ZDB-GENE-050913-117OMA, EggNOG
Zebrafish565370comtbcatechol-O-methyltransferase b7955ZDB-GENE-040724-164Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    transferase    /    methyltransferase    /    Catechol O-methyltransferase
DTO Classes
protein    /    Enzyme    /    Transferase    /    Methyltransferase    /    Catechol O-methyltransferase

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source