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VPS26A

DescriptionVacuolar protein sorting-associated protein 26A

Gene and Protein Information

Gene ID9559
Uniprot Accession IDs O75436 A8MZ56 B2RDD3 Q8TBH4 Q9H982
Ensembl ID ENSP00000362480
Symbol VPS26 HB58 PEP8A VPS26 Hbeta58
FamilyBelongs to the VPS26 family.
Sequence
MSFLGGFFGPICEIDIVLNDGETRKMAEMKTEDGKVEKHYLFYDGESVSGKVNLAFKQPGKRLEHQGIRIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRSYDFEFMQVEKPYESYIGANVRLRYFLKVTIVRRLTDLVKEYDLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAPEKLRKQRTNFHQRFESPESQASAEQPEM
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp748846VPS26AVPS26, retromer complex component A9598VGNC:7273OMA, EggNOG
Macaque717371VPS26AVPS26, retromer complex component A9544Inparanoid, OMA, EggNOG
Mouse30930Vps26aVPS26 retromer complex component A10090MGI:1353654Inparanoid, OMA, EggNOG
Rat361846Vps26aVPS26 retromer complex component A10116RGD:1359254Inparanoid, OMA
Dog479233VPS26AVPS26, retromer complex component A9615VGNC:48280Inparanoid, OMA, EggNOG
Horse100072671VPS26Avacuolar protein sorting 26 homolog A (S. pombe)9796OMA, EggNOG
Cow510574VPS26AVPS26, retromer complex component A9913VGNC:36814Inparanoid, OMA, EggNOG
Pig100155086VPS26AVPS26, retromer complex component A9823OMA, EggNOG
Opossum100031336VPS26AVPS26, retromer complex component A13616Inparanoid, OMA, EggNOG
PlatypusVPS26AVPS26, retromer complex component A [Source:HGNC Symbol;Acc:HGNC:12711]9258OMA, EggNOG
Chicken423696VPS26AVPS26, retromer complex component A9031CGNC:3064Inparanoid, OMA
Anole lizard100563088vps26aVPS26, retromer complex component A28377Inparanoid, OMA
Xenopus549925vps26aVPS26 retromer complex component A8364XB-GENE-944860Inparanoid, OMA
Zebrafish393881vps26aVPS26, retromer complex component A7955ZDB-GENE-040426-1108Inparanoid, OMA
C. elegans177764vps-26Vacuolar protein sorting-associated protein 266239Inparanoid, OMA
S.cerevisiae853393PEP8retromer subunit PEP84932S000003589Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    membrane traffic protein    /    Vacuolar protein sorting-associated protein 26A
DTO Classes
protein    /    Transporter    /    Vacuolar protein sorting-associated protein 26A

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details
Recombinant VPS26 AntibodyHuman,Mouse,Rat
  • WB
Out of Stock
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Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid
      dermatomyositis987Expression AtlasMONDO:0016367
      lung adenocarcinoma2873Expression AtlasMONDO:0005061
      multiple myeloma1334Expression AtlasMONDO:0009693
      ovarian cancer8576Expression AtlasMONDO:0008170
      Waldenstrons macroglobulinemia770Expression AtlasMONDO:0000432
      Diabetes Mellitus, Type 2290CTDMONDO:0005148
      mody290eRAMMONDO:0005148
      mody161eRAMMONDO:0018911
      Diabetes Mellitus, Non-Insulin-Dependent0DisGeNET

      Bibliography

      1.Zhang, Q H QH and 20 more authors. 2000-10 Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. [PMID:11042152]
      2.Haft, C R CR and 5 more authors. 2000-12 Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes. [PMID:11102511]
      3.Reddy, J V JV and Seaman, M N MN. 2001-10 Vps26p, a component of retromer, directs the interactions of Vps35p in endosome-to-Golgi retrieval. [PMID:11598206]
      4.Strausberg, Robert L RL and 83 more authors. 2002-12-24 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. [PMID:12477932]
      5.Ota, Toshio T and 156 more authors. 2004-01 Complete sequencing and characterization of 21,243 full-length human cDNAs. [PMID:14702039]
      6. and Seaman, Matthew N J MN. 2004-04 Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer. [PMID:15078902]
      7.Arighi, Cecilia N CN, Hartnell, Lisa M LM, Aguilar, Ruben C RC, Haft, Carol R CR and Bonifacino, Juan S JS. 2004-04 Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor. [PMID:15078903]
      8.Deloukas, P P and 135 more authors. 2004-05-27 The DNA sequence and comparative analysis of human chromosome 10. [PMID:15164054]
      9.Vergés, Marcel M and 8 more authors. 2004-08 The mammalian retromer regulates transcytosis of the polymeric immunoglobulin receptor. [PMID:15247922]
      10.Mingot, José-Manuel JM, Bohnsack, Markus T MT, Jäkle, Ursula U and Görlich, Dirk D. 2004-08-18 Exportin 7 defines a novel general nuclear export pathway. [PMID:15282546]