YTHDC2

Description3'-5' RNA helicase YTHDC2

Gene and Protein Information

Gene ID64848
Uniprot Accession IDs B2RP66
Ensembl ID ENSP00000161863
Symbol CAHL hYTHDC2
FamilyBelongs to the DEAD box helicase family. DEAH subfamily.
Sequence
MSRPSSVSPRQPAPGGGGGGGPSPCGPGGGGRAKGLKDIRIDEEVKIAVNIALERFRYGDQREMEFPSSLTSTERAFIHRLSQSLGLVSKSKGKGANRYLTVKKKDGSETAHAMMTCNLTHNTKHAVRSLIQRFPVTNKERTELLPKTERGNVFAVEAENREMSKTSGRLNNGIPQIPVKRGESEFDSFRQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCRIFCTQPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYIQGRPFEVKEMFLEDILRTTGYTNKEMLKYKKEKQQEEKQQTTLTEWYSAQENSFKPESQRQRTVLNVTDEYDLLDDGGDAVFSQLTEKDVNCLEPWLIKEMDACLSDIWLHKDIDAFAQVFHLILTENVSVDYRHSETSATALMVAAGRGFASQVEQLISMGANVHSKASNGWMALDWAKHFGQTEIVDLLESYSATLEFGNLDESSLVQTNGSDLSAEDRELLKAYHHSFDDEKVDLDLIMHLLYNICHSCDAGAVLIFLPGYDEIVGLRDRILFDDKRFADSTHRYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQKARSDGWERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYPNLVHVDRENLVLTGPKEKKVRFHPASVLSQPQYKKIPPANGQAAAIKALPTDWLIYDEMTRAHRIANIRCCSAVTPVTILVFCGPARLASNALQEPSSFRVDGIPNDSSDSEMEDKTTANLAALKLDEWLHFTLEPEAASLLLQLRQKWHSLFLRRMRAPSKPWSQVDEATIRAIIAVLSTEEQSAGLQQPSGIGQRPRPMSSEELPLASSWRSNNSRKSSADTEFSDECTTAERVLMKSPSPALHPPQKYKDRGILHPKRGTEDRSDQSSLKSTDSSSYPSPCASPSPPSSGKGSKSPSPRPNMPVRYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWESSIVYLVFSVQGSGHFQGFSRMSSEIGREKSQDWGSAGLGGVFKVEWIRKESLPFQFAHHLLNPWNDNKKVQISRDGQELEPLVGEQLLQLWERLPLGEKNTTD
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp462004YTHDC2YTH domain containing 29598VGNC:4228OMA, EggNOG
Macaque694612YTHDC2YTH domain containing 29544OMA, EggNOG
Mouse240255Ythdc2YTH domain containing 210090MGI:2448561Inparanoid, OMA, EggNOG
Rat307446Ythdc2YTH domain containing 210116RGD:1563192Inparanoid, OMA
Dog474641YTHDC2YTH domain containing 29615VGNC:48504Inparanoid, OMA, EggNOG
Horse100064372YTHDC2YTH domain containing 29796VGNC:25114Inparanoid, OMA, EggNOG
Cow541024YTHDC2YTH domain containing 29913VGNC:37040Inparanoid, OMA, EggNOG
Pig100519357YTHDC2YTH domain containing 29823OMA, EggNOG
Opossum100016147YTHDC2YTH domain containing 213616Inparanoid, OMA, EggNOG
Chicken415602YTHDC2YTH domain containing 29031CGNC:106Inparanoid, OMA, EggNOG
Anole lizard100555346ythdc2YTH domain containing 228377Inparanoid, OMA, EggNOG
Xenopusythdc2YTH domain containing 2 [Source:Xenbase;Acc:XB-GENE-5881731]8364OMA, EggNOG
C. elegans172615F52B5.3hypothetical protein6239OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    helicase    /    Probable ATP-dependent RNA helicase YTHDC2
protein    /    nucleic acid binding    /    RNA binding protein    /    Probable ATP-dependent RNA helicase YTHDC2
protein    /    nucleic acid binding    /    RNA helicase    /    Probable ATP-dependent RNA helicase YTHDC2
DTO Classes
protein    /    Enzyme    /    Helicase    /    RNA helicase    /    Probable ATP-dependent RNA helicase YTHDC2

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source