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UBA3
| Description | NEDD8-activating enzyme E1 catalytic subunit |
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Gene and Protein Information
| Gene ID | 9039 |
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| Uniprot Accession IDs | A6NLB5 A8K027 O76088 Q9NTU3 |
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| Ensembl ID | ENSP00000354340 |
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| Symbol | UBE1C NAE2 UBE1C hUBA3 |
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| Family | Belongs to the ubiquitin-activating E1 family. UBA3 subfamily. |
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| Sequence | MADGEEPEKKRRRIEELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIASMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDGDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAERKENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATLEGKNRTLYLQSVTSIEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFTS Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 460496 | UBA3 | ubiquitin like modifier activating enzyme 3 | 9598 | VGNC:7136 | OMA, EggNOG |
| Macaque | 696493 | UBA3 | ubiquitin like modifier activating enzyme 3 | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 22200 | Uba3 | ubiquitin-like modifier activating enzyme 3 | 10090 | MGI:1341217 | Inparanoid, OMA, EggNOG |
| Rat | 117553 | Uba3 | ubiquitin-like modifier activating enzyme 3 | 10116 | RGD:621084 | Inparanoid, OMA, EggNOG |
| Dog | 476560 | UBA3 | ubiquitin like modifier activating enzyme 3 | 9615 | VGNC:48038 | Inparanoid, OMA, EggNOG |
| Horse | 100053395 | UBA3 | ubiquitin like modifier activating enzyme 3 | 9796 | VGNC:24701 | Inparanoid, OMA, EggNOG |
| Cow | 512647 | UBA3 | ubiquitin like modifier activating enzyme 3 | 9913 | VGNC:36563 | Inparanoid, OMA, EggNOG |
| Pig | 100153428 | UBA3 | ubiquitin like modifier activating enzyme 3 | 9823 | | Inparanoid, OMA, EggNOG |
| Opossum | 100011849 | UBA3 | ubiquitin like modifier activating enzyme 3 | 13616 | | Inparanoid, OMA, EggNOG |
| Platypus | 100078310 | UBA3 | ubiquitin like modifier activating enzyme 3 | 9258 | | Inparanoid, OMA, EggNOG |
| Chicken | 426073 | UBA3 | ubiquitin like modifier activating enzyme 3 | 9031 | CGNC:52666 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100566540 | uba3 | ubiquitin like modifier activating enzyme 3 | 28377 | | Inparanoid, OMA, EggNOG |
| Xenopus | 100124303 | uba3 | ubiquitin like modifier activating enzyme 3 | 8364 | XB-GENE-947291 | Inparanoid, OMA, EggNOG |
| Zebrafish | 406776 | uba3 | ubiquitin-like modifier activating enzyme 3 | 7955 | ZDB-GENE-040426-2825 | Inparanoid, OMA, EggNOG |
| C. elegans | 175982 | rfl-1 | NEDD8-activating enzyme E1 catalytic subunit | 6239 | | Inparanoid, OMA, EggNOG |
| Fruitfly | 36539 | Uba3 | Ubiquitin activating enzyme 3 | 7227 | FBgn0263697 | Inparanoid, OMA, EggNOG |
| S.cerevisiae | 856179 | UBA3 | NEDD8-activating protein UBA3 | 4932 | S000006270 | Inparanoid, OMA, EggNOG |
Protein Classes
PANTHER Classes protein /
transfer/carrier protein / NEDD8-activating enzyme E1 catalytic subunit
protein /
ligase / NEDD8-activating enzyme E1 catalytic subunit
DTO Classes protein /
Enzyme /
Ligase / NEDD8-activating enzyme E1 catalytic subunit
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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