F11

DescriptionCoagulation factor XI

Gene and Protein Information

Gene ID2160
Uniprot Accession IDs D3DP64 Q4W5C2 Q9Y495 FXI
Ensembl ID ENSP00000384957
Symbol FXI PTA
FamilyBelongs to the peptidase S1 family. Plasma kallikrein subfamily.
Sequence
MIFLYQVVHFILFTSVSGECVTQLLKDTCFEGGDITTVFTPSAKYCQVVCTYHPRCLLFTFTAESPSEDPTRWFTCVLKDSVTETLPRVNRTAAISGYSFKQCSHQISACNKDIYVDLDMKGINYNSSVAKSAQECQERCTDDVHCHFFTYATRQFPSLEHRNICLLKHTQTGTPTRITKLDKVVSGFSLKSCALSNLACIRDIFPNTVFADSNIDSVMAPDAFVCGRICTHHPGCLFFTFFSQEWPKESQRNLCLLKTSESGLPSTRIKKSKALSGFSLQSCRHSIPVFCHSSFYHDTDFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCNEGKGKCYLKLSSNGSPTKILHGRGGISGYTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQAV
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp461643F11coagulation factor XI9598VGNC:2036OMA, EggNOG
Macaque702117F11coagulation factor XI9544OMA, EggNOG
Mouse109821F11coagulation factor XI10090MGI:99481Inparanoid, OMA, EggNOG
Dog475623F11coagulation factor XI9615VGNC:40544Inparanoid, OMA
Horse100056603F11coagulation factor XI9796VGNC:17753Inparanoid, OMA
Cow407998F11coagulation factor XI9913VGNC:28678Inparanoid, OMA
Anole lizard100557428klkb1kallikrein B128377Inparanoid, OMA
Xenopus100486524klkb1kallikrein B18364XB-GENE-985051Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    serine protease    /    Coagulation factor XI
DTO Classes
protein    /    Enzyme    /    Protease    /    Serine protease    /    Coagulation factor XI

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source