WNK1
| Description | Serine/threonine-protein kinase WNK1 |
|---|
Gene and Protein Information
| Gene ID | 65125 |
|---|---|
| Uniprot Accession IDs | A1L4B0 C5HTZ5 C5HTZ6 C5HTZ7 H6WZW3 O15052 P54963 Q4VBX9 Q6IFS5 Q86WL5 Q8N673 Q96CZ6 Q9P1S9 |
| Ensembl ID | ENSP00000341292 |
| Symbol | HSN2 KDP KIAA0344 PRKWNK1 KDP PSK p65 HSN2 HSAN2 PRKWNK1 PPP1R167 |
| Family | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WNK subfamily. |
| Sequence | MSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGAAAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQPLPTPLLPQYPVSQIPISTPHVSTAQTGFSSLPITMAAGITQPLLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQVAPAEPVAVAQTQATQPTTLASSVDSAHSDVASGMSDGNENVPSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLCIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRFQVTTTANKVGRFSVSKTEDKITDTKKEGPVASPPFMDLEQAVLPAVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVDDGSGSPHSPHQLSSKSLPSQNLSQSLSNSFNSSYMSSDNESDIEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIESLYTKLGKVPPAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLGNKSPQLSGNLSGQSAASVLHPQQTLHPPGNIPESGQNQLLQPLKPSPSSDNLYSAFTSDGAISVPSLSAPGQGTSSTNTVGATVNSQAAQAQPPAMTSSRKGTFTDDLHKLVDNWARDAMNLSGRRGSKGHMNYEGPGMARKFSAPGQLCISMTSNLGGSAPISAASATSLGHFTKSMCPPQQYGFPATPFGAQWSGTGGPAPQPLGQFQPVGTASLQNFNISNLQKSISNPPGSNLRTT Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 451739 | WNK1 | WNK lysine deficient protein kinase 1 | 9598 | VGNC:13495 | Inparanoid, OMA, EggNOG |
| Macaque | 706493 | WNK1 | WNK lysine deficient protein kinase 1 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 232341 | Wnk1 | WNK lysine deficient protein kinase 1 | 10090 | MGI:2442092 | Inparanoid, OMA, EggNOG |
| Rat | 116477 | Wnk1 | WNK lysine deficient protein kinase 1 | 10116 | RGD:621141 | Inparanoid, OMA, EggNOG |
| Dog | 477728 | WNK1 | WNK lysine deficient protein kinase 1 | 9615 | VGNC:48418 | Inparanoid, OMA, EggNOG |
| Horse | 100056745 | WNK1 | WNK lysine deficient protein kinase 1 | 9796 | VGNC:52460 | Inparanoid, OMA, EggNOG |
| Cow | 506433 | WNK1 | WNK lysine deficient protein kinase 1 | 9913 | VGNC:36949 | Inparanoid, OMA, EggNOG |
| Pig | 406235 | WNK1 | WNK lysine deficient protein kinase 1 | 9823 | OMA, EggNOG | |
| Opossum | 100017207 | WNK1 | WNK lysine deficient protein kinase 1 | 13616 | Inparanoid, OMA, EggNOG | |
| Chicken | 427925 | WNK1 | WNK lysine deficient protein kinase 1 | 9031 | CGNC:9833 | OMA, EggNOG |
| Anole lizard | 100552658 | wnk1 | WNK lysine deficient protein kinase 1 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100036683 | wnk1 | WNK lysine deficient protein kinase 1 | 8364 | XB-GENE-877004 | Inparanoid, OMA, EggNOG |
| Zebrafish | 561159 | wnk1b | WNK lysine deficient protein kinase 1b | 7955 | ZDB-GENE-030131-2656 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / non-receptor serine/threonine protein kinase / Serine/threonine-protein kinase wnk1
protein / protein kinase / Serine/threonine-protein kinase wnk1
protein / transferase / Serine/threonine-protein kinase wnk1
protein / kinase / Serine/threonine-protein kinase wnk1
protein / non-receptor serine/threonine protein kinase / Serine/threonine-protein kinase wnk1
protein / protein kinase / Serine/threonine-protein kinase wnk1
protein / transferase / Serine/threonine-protein kinase wnk1
protein / kinase / Serine/threonine-protein kinase wnk1
DTO Classes
protein / Kinase / Protein kinase / Other group / WNK family / Serine/threonine-protein kinase wnk1
protein / Kinase / Protein kinase / Other group / WNK family / Serine/threonine-protein kinase wnk1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
|---|
Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
|---|
Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
|---|
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
|---|