UBA1

Description	Ubiquitin-like modifier-activating enzyme 1

Gene and Protein Information

Gene ID	7317
Uniprot Accession IDs	Q5JRR8 Q96E13
Ensembl ID	ENSP00000338413
Symbol	A1S9T UBE1 A1S9 A1ST GXP1 UBE1 A1S9T AMCX1 POC20 SMAX2 UBA1A UBE1X CFAP124
Family	Belongs to the ubiquitin-activating E1 family.
Sequence	MSSSPLSKKRRVSGPDPKPGSNCSPAQSVLSEVPSVPTNGMAKNGSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQVVVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQALHQFCAQHGRPPRPRNEEDAAELVALAQAVNARALPAVQQNNLDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPIMQWLYFDALECLPEDKEVLTEDKCLQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQPAENVNQYLTDPKFVERTLRLAGTQPLEVLEAVQRSLVLQRPQTWADCVTWACHHWHTQYSNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNPLHLDYVMAAANLFAQTYGLTGSQDRAAVATFLQSVQVPEFTPKSGVKIHVSDQELQSANASVDDSRLEELKATLPSPDKLPGFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDIPSADRHKSKLIAGKIIPAIATTTAAVVGLVCLELYKVVQGHRQLDSYKNGFLNLALPFFGFSEPLAAPRHQYYNQEWTLWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTIR Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Macaque	706324	UBA1	ubiquitin like modifier activating enzyme 1	9544		Inparanoid, OMA, EggNOG
Mouse	22201	Uba1	ubiquitin-like modifier activating enzyme 1	10090	MGI:98890	Inparanoid, OMA, EggNOG
Rat	314432	Uba1	ubiquitin-like modifier activating enzyme 1	10116	RGD:1359327	Inparanoid, OMA, EggNOG
Dog	480896	UBA1	ubiquitin like modifier activating enzyme 1	9615	VGNC:48036	Inparanoid, OMA, EggNOG
Horse	100060792	UBA1	ubiquitin like modifier activating enzyme 1	9796	VGNC:24699	Inparanoid, OMA, EggNOG
Cow	282869	UBA1	ubiquitin like modifier activating enzyme 1	9913	VGNC:36561	Inparanoid, OMA, EggNOG
Pig	100525439	UBA1	ubiquitin like modifier activating enzyme 1	9823		Inparanoid, OMA, EggNOG
Opossum	100012835	UBA1	ubiquitin like modifier activating enzyme 1	13616		Inparanoid, OMA, EggNOG
Anole lizard	100552704	uba1	ubiquitin like modifier activating enzyme 1	28377		Inparanoid, OMA
Zebrafish	406335	uba1	ubiquitin-like modifier activating enzyme 1	7955	ZDB-GENE-040426-2009	Inparanoid, OMA, EggNOG
C. elegans	177855	uba-1	UBA (human ubiquitin) related	6239		Inparanoid, OMA, EggNOG
Fruitfly	35998	Uba1	Ubiquitin activating enzyme 1	7227	FBgn0023143	Inparanoid, EggNOG
S.cerevisiae	853670	UBA1	E1 ubiquitin-activating protein UBA1	4932	S000001693	Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein / transfer/carrier protein / Ubiquitin-like modifier-activating enzyme 1
protein / ligase / Ubiquitin-like modifier-activating enzyme 1

DTO Classes
protein / Enzyme / Ligase / Ubiquitin-like modifier-activating enzyme 1

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source