EXO1

DescriptionExonuclease 1

Gene and Protein Information

Gene ID9156
Uniprot Accession IDs O60545 O75214 O75466 Q5T396 Q96IJ1 Q9UG38 Q9UNW0 hExo1
Ensembl ID ENSP00000355506
Symbol EXOI HEX1 HEX1 hExoI
FamilyBelongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
Sequence
MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFTRSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNAYEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKTCQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRPRSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTRNKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHESEYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPPTLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESSDDESHPLREEACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTSKLRLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHNAENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRVQRAIFQ
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp457856EXO1exonuclease 19598VGNC:1236OMA, EggNOG
Macaque706902EXO1exonuclease 19544Inparanoid, OMA, EggNOG
Mouse26909Exo1exonuclease 110090MGI:1349427Inparanoid, OMA, EggNOG
Rat305000Exo1exonuclease 110116RGD:1309465Inparanoid, OMA
Dog100855525EXO1exonuclease 19615VGNC:40511Inparanoid, OMA, EggNOG
Horse100054824EXO1exonuclease 19796VGNC:17716Inparanoid, OMA, EggNOG
Cow506390EXO1exonuclease 19913VGNC:28642Inparanoid, OMA, EggNOG
Pig100512301EXO1exonuclease 19823Inparanoid, OMA, EggNOG
Opossum100020408EXO1exonuclease 113616Inparanoid, OMA, EggNOG
Chicken421505EXO1exonuclease 19031CGNC:8172Inparanoid, OMA, EggNOG
Anole lizard100564366exo1exonuclease 128377Inparanoid, OMA
Xenopus100487930exo1exonuclease 18364XB-GENE-982078Inparanoid, EggNOG
Zebrafish406778exo1exonuclease 17955ZDB-GENE-040426-2828Inparanoid, OMA, EggNOG
C. elegans176765exo-1EXOnuclease6239Inparanoid, EggNOG
Fruitfly35119tostosca7227FBgn0015553Inparanoid, EggNOG

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    damaged DNA-binding protein    /    Exonuclease 1
protein    /    nucleic acid binding    /    exodeoxyribonuclease    /    Exonuclease 1
protein    /    nucleic acid binding    /    nuclease    /    Exonuclease 1
protein    /    nucleic acid binding    /    endodeoxyribonuclease    /    Exonuclease 1
protein    /    nucleic acid binding    /    hydrolase    /    Exonuclease 1
DTO Classes
protein    /    Enzyme    /    Nuclease    /    Exodeoxyribonuclease    /    Exonuclease 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source