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KDR
| Description | Vascular endothelial growth factor receptor 2 |
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Gene and Protein Information
| Gene ID | 3791 |
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| Uniprot Accession IDs | A2RRS0 B5A925 C5IFA0 O60723 Q14178 VEGFR-2 |
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| Ensembl ID | ENSP00000263923 |
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| Symbol | FLK1 VEGFR2 FLK1 CD309 VEGFR VEGFR2 |
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| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. |
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| Sequence | MQSKVLLAVALWLCVETRAASVGLPSVSLDLPRLSIQKDILTIKANTTLQITCRGQRDLDWLWPNNQSGSEQRVEVTECSDGLFCKTLTIPKVIGNDTGAYKCFYRETDLASVIYVYVQDYRSPFIASVSDQHGVVYITENKNKTVVIPCLGSISNLNVSLCARYPEKRFVPDGNRISWDSKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYRIYDVVLSPSHGIELSVGEKLVLNCTARTELNVGIDFNWEYPSSKHQHKKLVNRDLKTQSGSEMKKFLSTLTIDGVTRSDQGLYTCAASSGLMTKKNSTFVRVHEKPFVAFGSGMESLVEATVGERVRIPAKYLGYPPPEIKWYKNGIPLESNHTIKAGHVLTIMEVSERDTGNYTVILTNPISKEKQSHVVSLVVYVPPQIGEKSLISPVDSYQYGTTQTLTCTVYAIPPPHHIHWYWQLEEECANEPSQAVSVTNPYPCEEWRSVEDFQGGNKIEVNKNQFALIEGKNKTVSTLVIQAANVSALYKCEAVNKVGRGERVISFHVTRGPEITLQPDMQPTEQESVSLWCTADRSTFENLTWYKLGPQPLPIHVGELPTPVCKNLDTLWKLNATMFSNSTNDILIMELKNASLQDQGDYVCLAQDRKTKKRHCVVRQLTVLERVAPTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVLKDGNRNLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIEGAQEKTNLEIIILVGTAVIAMFFWLLLVIILRTVKRANGGELKTGYLSIVMDPDELPLDEHCERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKTATCRTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKTKGARFRQGKDYVGAIPVDLKRRLDSITSSQSSASSGFVEEKSLSDVEEEEAPEDLYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDGKDYIVLPISETLSMEEDSGLSLPTSPVSCMEEEEVCDPKFHYDNTAGISQYLQNSKRKSRPVSVKTFEDIPLEEPEVKVIPDDNQTDSGMVLASEELKTLEDRTKLSPSFGGMVPSKSRESVASEGSNQTSGYQSGYHSDDTDTTVYSSEEAELLKLIEIGVQTGSTAQILQPDSGTTLSSPPV Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 461315 | KDR | kinase insert domain receptor | 9598 | VGNC:755 | OMA, EggNOG |
| Macaque | 698293 | KDR | kinase insert domain receptor | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 16542 | Kdr | kinase insert domain protein receptor | 10090 | MGI:96683 | Inparanoid, OMA, EggNOG |
| Rat | 25589 | Kdr | kinase insert domain receptor | 10116 | RGD:2965 | Inparanoid, OMA |
| Dog | 482154 | KDR | kinase insert domain receptor | 9615 | VGNC:42331 | Inparanoid, OMA, EggNOG |
| Horse | 100033959 | KDR | kinase insert domain receptor | 9796 | VGNC:19344 | Inparanoid, OMA, EggNOG |
| Cow | 407170 | KDR | kinase insert domain receptor | 9913 | VGNC:30535 | Inparanoid, OMA, EggNOG |
| Pig | 397311 | KDR | kinase insert domain receptor | 9823 | | Inparanoid, OMA, EggNOG |
| Opossum | 100017311 | KDR | kinase insert domain receptor | 13616 | | Inparanoid, OMA, EggNOG |
| Platypus | | KDR | kinase insert domain receptor [Source:HGNC Symbol;Acc:HGNC:6307] | 9258 | | OMA, EggNOG |
| Chicken | 395323 | KDR | kinase insert domain receptor | 9031 | CGNC:10404 | Inparanoid, OMA |
| Anole lizard | 100551738 | kdr | kinase insert domain receptor | 28377 | | Inparanoid, OMA |
| Xenopus | 100487501 | kdr | kinase insert domain receptor | 8364 | XB-GENE-6053213 | Inparanoid, OMA |
| Zebrafish | 554230 | kdr | kinase insert domain receptor (a type III receptor tyrosine kinase) | 7955 | ZDB-GENE-041001-112 | Inparanoid, OMA |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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