CHRNA5

DescriptionNeuronal acetylcholine receptor subunit alpha-5

Gene and Protein Information

Gene ID1138
Uniprot Accession IDs Q15824 Q99554
Ensembl ID ENSP00000299565
Symbol NACHRA5 LNCR2
FamilyBelongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-5/CHRNA5 sub-subfamily.
Sequence
MAARGSGPRALRLLLLVQLVAGRCGLAGAAGGAQRGLSEPSSIAKHEDSLLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDFFDNGEWEIVSATGSKGNRTDSCCWYPYVTYSFVIKRLPLFYTLFLIIPCIGLSFLTVLVFYLPSNEGEKICLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIMVTVFAINIHHRSSSTHNAMAPLVRKIFLHTLPKLLCMRSHVDRYFTQKEETESGSGPKSSRNTLEAALDSIRYITRHIMKENDVREVVEDWKFIAQVLDRMFLWTFLFVSIVGSLGLFVPVIYKWANILIPVHIGNANK
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp619369CHRNA5cholinergic receptor nicotinic alpha 5 subunit9598VGNC:10796Inparanoid, OMA, EggNOG
Macaque574191CHRNA5cholinergic receptor nicotinic alpha 5 subunit9544Inparanoid, OMA, EggNOG
Mouse110835Chrna5cholinergic receptor, nicotinic, alpha polypeptide 510090MGI:87889Inparanoid, OMA, EggNOG
Rat25102Chrna5cholinergic receptor nicotinic alpha 5 subunit10116RGD:2347Inparanoid, OMA, EggNOG
Dog482112CHRNA5cholinergic receptor nicotinic alpha 5 subunit9615VGNC:49739Inparanoid, OMA, EggNOG
Horse100060416CHRNA5cholinergic receptor nicotinic alpha 5 subunit9796VGNC:51482Inparanoid, OMA, EggNOG
Cow282177CHRNA5cholinergic receptor nicotinic alpha 5 subunit9913VGNC:27327Inparanoid, OMA, EggNOG
Pig100156023CHRNA5cholinergic receptor nicotinic alpha 5 subunit9823OMA, EggNOG
Opossum100025774CHRNA5cholinergic receptor nicotinic alpha 5 subunit13616Inparanoid, EggNOG
PlatypusCHRNA5cholinergic receptor nicotinic alpha 5 subunit [Source:HGNC Symbol;Acc:HGNC:1959]9258OMA, EggNOG
Chicken386577CHRNA5cholinergic receptor nicotinic alpha 5 subunit9031CGNC:49155Inparanoid, OMA
Xenopus100379824chrna5cholinergic receptor nicotinic alpha 5 subunit8364XB-GENE-5755296Inparanoid, OMA
Zebrafish550584chrna5cholinergic receptor, nicotinic, alpha 57955ZDB-GENE-050417-440Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    transporter    /    ligand-gated ion channel    /    Neuronal acetylcholine receptor subunit alpha-5
protein    /    transporter    /    ion channel    /    Neuronal acetylcholine receptor subunit alpha-5
protein    /    transporter    /    acetylcholine receptor    /    Neuronal acetylcholine receptor subunit alpha-5
protein    /    transporter    /    GABA receptor    /    Neuronal acetylcholine receptor subunit alpha-5
protein    /    transporter    /    receptor    /    Neuronal acetylcholine receptor subunit alpha-5
DTO Classes
protein    /    Ion channel    /    Neurotransmitter receptor, Cys loop, ligand-gated ion channel (LIC) family    /    Acetylcholine receptor subfamily    /    Alpha-5/CHRNA5 sub-subfamily    /    Neuronal acetylcholine receptor subunit alpha-5

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Pathway

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