ACVR1

DescriptionActivin receptor type-1

Gene and Protein Information

Gene ID90
Uniprot Accession IDs Q04771
Ensembl ID ENSP00000263640
Symbol ACVRLK2 FOP ALK2 SKR1 TSRI ACTRI ACVR1A ACVRLK2
FamilyBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Sequence
MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSINDGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNFHLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTLADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKIDNSLDKLKTDC
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp470565ACVR1activin A receptor type 19598VGNC:56OMA, EggNOG
Macaque697935ACVR1activin A receptor type 19544Inparanoid, OMA, EggNOG
Mouse11477Acvr1activin A receptor, type 110090MGI:87911Inparanoid, OMA, EggNOG
Rat79558Acvr1activin A receptor type 110116RGD:620200Inparanoid, OMA, EggNOG
Dog478757ACVR1activin A receptor type 19615VGNC:37561Inparanoid, OMA
Horse100050899ACVR1activin A receptor type 19796VGNC:15035Inparanoid, OMA
Cow338068ACVR1activin A receptor type 19913VGNC:25592Inparanoid, OMA
Pig100152307ACVR1activin A receptor type 19823Inparanoid, OMA
Opossum100021438ACVR1activin A receptor type 113616Inparanoid, OMA
Anole lizard100552279acvr1activin A receptor type 128377Inparanoid, OMA
Xenopus550111acvr1activin A receptor type 18364XB-GENE-478850Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    receptor    /    protein kinase receptor    /    Activin receptor type-1
protein    /    receptor    /    TGF-beta receptor    /    Activin receptor type-1
protein    /    receptor    /    serine/threonine protein kinase receptor    /    Activin receptor type-1
protein    /    receptor    /    protein kinase    /    Activin receptor type-1
protein    /    receptor    /    transferase    /    Activin receptor type-1
protein    /    receptor    /    kinase    /    Activin receptor type-1
DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    STKR family    /    STKR Type 1 subfamily    /    Activin receptor type-1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source