TNK2

DescriptionActivated CDC42 kinase 1

Gene and Protein Information

Gene ID10188
Uniprot Accession IDs Q6ZMQ0 Q8N6U7 Q96H59 ACK-1
Ensembl ID ENSP00000371341
Symbol ACK1 ACK ACK1 ACK-1 p21cdc42Hs
FamilyBelongs to the protein kinase superfamily. Tyr protein kinase family.
Sequence
MQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVTRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKRRKALCKRKSWMSKVFSGKRLEAEFPPHHSQSTFRKTSPAPGGPAGEGPLQSLTCLIGEKDLRLLEKLGDGSFGVVRRGEWDAPSGKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLEAQPTDMRALQDFEEPDKLHIQMNDVITVIEGRAENYWWRGQNTRTLCVGPFPRNVVTSVAGLSAQDISQPLQNSFIHTGHGDSDPRHCWGFPDRIDELYLGNPMDPPDLLSVELSTSRPPQHLGGVKKPTYDPVSEDQDPLSSDFKRLGLRKPGLPRGLWLAKPSARVPGTKASRGSGAEVTLIDFGEEPVVPALRPCAPSLAQLAMDACSLLDETPPQSPTRALPRPLHPTPVVDWDARPLPPPPAYDDVAQDEDDFEICSINSTLVGAGVPAGPSQGQTNYAFVPEQARPPPPLEDNLFLPPQGGGKPPSSAQTAEIFQALQQECMRQLQAPAGSPAPSPSPGGDDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPRVPPREPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTTQSFASDPKYATPQVIQAPGPRAGPCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQSPEEPTPLPVPLLLPPPSTPAPAAPTATVRPMPQAALDPKANFSTNNSNPGARPPPPRATARLPQRGCPGDGPEAGRPADKIQMAMVHGVTTEECQAALQCHGWSVQRAAQYLKVEQLFGLGLRPRGECHKVLEMFDWNLEQAGCHLLGSWGPAHHKR
Show more
Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Macaque711655TNK2tyrosine kinase non receptor 29544Inparanoid, OMA, EggNOG
Mouse51789Tnk2tyrosine kinase, non-receptor, 210090MGI:1858308Inparanoid, OMA, EggNOG
Rat303882Tnk2tyrosine kinase, non-receptor, 210116RGD:1305957Inparanoid, OMA, EggNOG
Dog488025TNK2tyrosine kinase non receptor 29615VGNC:47680Inparanoid, OMA, EggNOG
HorseTNK2tyrosine kinase non receptor 2 [Source:HGNC Symbol;Acc:HGNC:19297]9796OMA, EggNOG
Cow280710TNK2tyrosine kinase non receptor 29913VGNC:36183Inparanoid, OMA, EggNOG
Pig100513310TNK2tyrosine kinase non receptor 29823Inparanoid, OMA, EggNOG
Opossum100021602TNK2tyrosine kinase non receptor 213616Inparanoid, OMA, EggNOG
Xenopus100124754tnk2tyrosine kinase, non-receptor, 28364XB-GENE-984470Inparanoid, OMA
Zebrafish559119tnk2btyrosine kinase, non-receptor, 2b7955ZDB-GENE-110411-165Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TK group    /    ACK family    /    Activated cdc42 kinase 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source