CHRNA1

DescriptionAcetylcholine receptor subunit alpha

Gene and Protein Information

Gene ID1134
Uniprot Accession IDs B4DRV6 D3DPE8
Ensembl ID ENSP00000261007
Symbol ACHRA CHNRA ACHRA ACHRD CHRNA CMS1A CMS1B CMS2A FCCMS SCCMS
FamilyBelongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-1/CHRNA1 sub-subfamily.
Sequence
MEPWPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEVNQIVTTNVRLKQGDMVDLPRPSCVTLGVPLFSHLQNEQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNADGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKESRGWKHSVTYSCCPDTPYLDITYHFVMQRLPLYFIVNVIIPCLLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIVINTHHRSPSTHVMPNWVRKVFIDTIPNIMFFSTMKRPSREKQDKKIFTEDIDISDISGKPGPPPMGFHSPLIKHPEVKSAIEGIKYIAETMKSDQESNNAAAEWKYVAMVMDHILLGVFMLVCIIGTLAVFAGRLIELNQQG
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp470583CHRNA1cholinergic receptor nicotinic alpha 1 subunit9598VGNC:136OMA, EggNOG
Macaque698578CHRNA1cholinergic receptor nicotinic alpha 1 subunit9544Inparanoid, OMA, EggNOG
Mouse11435Chrna1cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)10090MGI:87885Inparanoid, OMA, EggNOG
Rat79557Chrna1cholinergic receptor nicotinic alpha 1 subunit10116RGD:69277Inparanoid, OMA, EggNOG
Dog403757CHRNA1cholinergic receptor nicotinic alpha 1 subunit9615VGNC:39236Inparanoid, OMA, EggNOG
Horse100065034CHRNA1cholinergic receptor nicotinic alpha 1 subunit9796VGNC:16522Inparanoid, OMA, EggNOG
Cow338070CHRNA1cholinergic receptor nicotinic alpha 1 subunit9913VGNC:27322Inparanoid, OMA, EggNOG
Opossum100025856CHRNA1cholinergic receptor nicotinic alpha 1 subunit13616Inparanoid, OMA, EggNOG
Platypus100084387CHRNA1cholinergic receptor nicotinic alpha 1 subunit9258Inparanoid, OMA, EggNOG
Chicken395608CHRNA1cholinergic receptor nicotinic alpha 1 subunit9031CGNC:7068Inparanoid, OMA
Anole lizard100557909chrna1cholinergic receptor nicotinic alpha 1 subunit28377Inparanoid, OMA, EggNOG
Xenopus100145177chrna1cholinergic receptor, nicotinic alpha 18364XB-GENE-977139Inparanoid, OMA, EggNOG
Zebrafish30725chrna1cholinergic receptor, nicotinic, alpha 1 (muscle)7955ZDB-GENE-980526-137Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    transporter    /    ligand-gated ion channel    /    Acetylcholine receptor subunit alpha
protein    /    transporter    /    ion channel    /    Acetylcholine receptor subunit alpha
protein    /    transporter    /    acetylcholine receptor    /    Acetylcholine receptor subunit alpha
protein    /    transporter    /    GABA receptor    /    Acetylcholine receptor subunit alpha
protein    /    transporter    /    receptor    /    Acetylcholine receptor subunit alpha
DTO Classes
protein    /    Ion channel    /    Neurotransmitter receptor, Cys loop, ligand-gated ion channel (LIC) family    /    Acetylcholine receptor subfamily    /    Alpha-1/CHRNA1 sub-subfamily    /    Acetylcholine receptor subunit alpha

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

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