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Protein or Target Summary

DNA-(apurinic or apyrimidinic site) lyase

Gene ID328
uniprotP27695
Gene NameAPEX1
Ensernbl IDENSP00000216714
FamilyBelongs to the DNA repair enzymes AP/ExoA family.
Sequence
MPKRGKKGAVAEDGDELRTEPEAKKSKTAAKKNDKEAAGEGPALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN328APEX1DNA-(apurinic or apyrimidinic site) lyaseP27695
MOUSEApex1DNA-(apurinic or apyrimidinic site) lyaseD3Z124
MOUSEApex1DNA-(apurinic or apyrimidinic site) lyaseF6QA74
MOUSEApex1DNA-(apurinic or apyrimidinic site) lyaseD3Z6R9
MOUSE11792Apex1DNA-(apurinic or apyrimidinic site) lyaseQ544Z7
MOUSE11792Apex1DNA-(apurinic or apyrimidinic site) lyaseP28352
RAT79116Apex1DNA-(apurinic or apyrimidinic site) lyaseP43138

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source
      Source: DataSourcesLicenses.xlsx
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