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APEX1
| Description | DNA-(apurinic or apyrimidinic site) lyase |
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Gene and Protein Information
| Gene ID | 328 |
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| Uniprot Accession IDs | Q969L5 Q99775 |
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| Ensembl ID | ENSP00000216714 |
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| Symbol | APE APE1 APEX APX HAP1 REF1 APE APX APE1 APEN APEX HAP1 REF1 |
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| Family | Belongs to the DNA repair enzymes AP/ExoA family. |
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| Sequence | MPKRGKKGAVAEDGDELRTEPEAKKSKTAAKKNDKEAAGEGPALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 465200 | APEX1 | apurinic/apyrimidinic endodeoxyribonuclease 1 | 9598 | VGNC:8393 | Inparanoid, OMA, EggNOG |
| Mouse | 11792 | Apex1 | apurinic/apyrimidinic endonuclease 1 | 10090 | MGI:88042 | Inparanoid, OMA, EggNOG |
| Rat | 79116 | Apex1 | apurinic/apyrimidinic endodeoxyribonuclease 1 | 10116 | RGD:2126 | Inparanoid, OMA, EggNOG |
| Dog | 482558 | APEX1 | apurinic/apyrimidinic endodeoxyribonuclease 1 | 9615 | VGNC:54195 | Inparanoid, OMA, EggNOG |
| Horse | 100072588 | APEX1 | apurinic/apyrimidinic endodeoxyribonuclease 1 | 9796 | VGNC:15404 | Inparanoid, OMA, EggNOG |
| Cow | 281630 | APEX1 | apurinic/apyrimidinic endodeoxyribonuclease 1 | 9913 | VGNC:26011 | Inparanoid, OMA, EggNOG |
| Opossum | 100029539 | APEX1 | apurinic/apyrimidinic endodeoxyribonuclease 1 | 13616 | | Inparanoid, EggNOG |
| Anole lizard | 100554177 | apex1 | apurinic/apyrimidinic endodeoxyribonuclease 1 | 28377 | | Inparanoid, OMA, EggNOG |
| Xenopus | 394929 | apex1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | 8364 | XB-GENE-977072 | Inparanoid, OMA, EggNOG |
| Zebrafish | 406730 | apex1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | 7955 | ZDB-GENE-040426-2761 | Inparanoid, OMA, EggNOG |
| C. elegans | 173069 | exo-3 | DNA-(apurinic or apyrimidinic site) lyase | 6239 | | Inparanoid, OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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