| Description | Bile salt export pump |
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Gene and Protein Information
| Gene ID | 8647 |
|---|---|
| Uniprot Accession IDs | Q53TL2 Q9UNB2 |
| Ensembl ID | ENSP00000263817 |
| Symbol | BSEP BSEP PGY4 SPGP ABC16 BRIC2 PFIC2 PFIC-2 |
| Family | Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily. |
| Sequence | MSDSVILRSIKKFGEENDGFESDKSYNNDKKSRLQDEKKGDGVRVGFFQLFRFSSSTDIWLMFVGSLCAFLHGIAQPGVLLIFGTMTDVFIDYDVELQELQIPGKACVNNTIVWTNSSLNQNMTNGTRCGLLNIESEMIKFASYYAGIAVAVLITGYIQICFWVIAAARQIQKMRKFYFRRIMRMEIGWFDCNSVGELNTRFSDDINKINDAIADQMALFIQRMTSTICGFLLGFFRGWKLTLVIISVSPLIGIGAATIGLSVSKFTDYELKAYAKAGVVADEVISSMRTVAAFGGEKREVERYEKNLVFAQRWGIRKGIVMGFFTGFVWCLIFLCYALAFWYGSTLVLDEGEYTPGTLVQIFLSVIVGALNLGNASPCLEAFATGRAAATSIFETIDRKPIIDCMSEDGYKLDRIKGEIEFHNVTFHYPSRPEVKILNDLNMVIKPGEMTALVGPSGAGKSTALQLIQRFYDPCEGMVTVDGHDIRSLNIQWLRDQIGIVEQEPVLFSTTIAENIRYGREDATMEDIVQAAKEANAYNFIMDLPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEVLSKIQHGHTIISVAHRLSTVRAADTIIGFEHGTAVERGTHEELLERKGVYFTLVTLQSQGNQALNEEDIKDATEDDMLARTFSRGSYQDSLRASIRQRSKSQLSYLVHEPPLAVVDHKSTYEEDRKDKDIPVQEEVEPAPVRRILKFSAPEWPYMLVGSVGAAVNGTVTPLYAFLFSQILGTFSIPDKEEQRSQINGVCLLFVAMGCVSLFTQFLQGYAFAKSGELLTKRLRKFGFRAMLGQDIAWFDDLRNSPGALTTRLATDASQVQGAAGSQIGMIVNSFTNVTVAMIIAFSFSWKLSLVILCFFPFLALSGATQTRMLTGFASRDKQALEMVGQITNEALSNIRTVAGIGKERRFIEALETELEKPFKTAIQKANIYGFCFAFAQCIMFIANSASYRYGGYLISNEGLHFSYVFRVISAVVLSATALGRAFSYTPSYAKAKISAARFFQLLDRQPPISVYNTAGEKWDNFQGKIDFVDCKFTYPSRPDSQVLNGLSVSISPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGKVMIDGHDSKKVNVQFLRSNIGIVSQEPVLFACSIMDNIKYGDNTKEIPMERVIAAAKQAQLHDFVMSLPEKYETNVGSQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQVALDKAREGRTCIVIAHRLSTIQNADIIAVMAQGVVIEKGTHEELMAQKGAYYKLVTTGSPIS Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Macaque | 709261 | ABCB11 | ATP binding cassette subfamily B member 11 | 9544 | Inparanoid, OMA | |
| Mouse | 27413 | Abcb11 | ATP-binding cassette, sub-family B (MDR/TAP), member 11 | 10090 | MGI:1351619 | Inparanoid, OMA |
| Rat | 83569 | Abcb11 | ATP binding cassette subfamily B member 11 | 10116 | RGD:619930 | Inparanoid, OMA |
| Dog | 488390 | ABCB11 | ATP binding cassette subfamily B member 11 | 9615 | VGNC:37433 | Inparanoid, OMA |
| Horse | 100052359 | ABCB11 | ATP binding cassette subfamily B member 11 | 9796 | VGNC:14909 | Inparanoid, OMA |
| Cow | 531150 | ABCB11 | ATP binding cassette subfamily B member 11 | 9913 | VGNC:25463 | Inparanoid, OMA |
| Pig | 100518154 | ABCB11 | ATP binding cassette subfamily B member 11 | 9823 | Inparanoid, OMA | |
| Opossum | 100024107 | ABCB11 | ATP binding cassette subfamily B member 11 | 13616 | Inparanoid, OMA | |
| Chicken | 424170 | ABCB11 | ATP binding cassette subfamily B member 11 | 9031 | CGNC:8276 | Inparanoid, OMA |
| Zebrafish | 571189 | abcb11b | ATP-binding cassette, sub-family B (MDR/TAP), member 11b | 7955 | ZDB-GENE-050517-14 | Inparanoid, OMA |
| C. elegans | 178215 | pgp-1 | Multidrug resistance protein pgp-1 | 6239 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / serine protease / Bile salt export pump
protein / cysteine protease / Bile salt export pump
protein / serine protease / Bile salt export pump
protein / cysteine protease / Bile salt export pump
DTO Classes
protein / Transporter / ATP-binding cassette transporter family / ABCB subfamily / Bile salt export pump
protein / Transporter / ATP-binding cassette transporter family / ABCB subfamily / Bile salt export pump
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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