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ALK
| Description | ALK tyrosine kinase receptor |
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Gene and Protein Information
| Gene ID | 238 |
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| Uniprot Accession IDs | Q4ZFX9 Q53QQ6 Q53RZ4 Q59FI3 Q9Y4K6 |
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| Ensembl ID | ENSP00000373700 |
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| Symbol | CD246 NBLST3 |
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| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily. |
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| Sequence | MGAIGLLWLLPLLLSTAAVGSGMGTGQRAGSPAAGPPLQPREPLSYSRLQRKSLAVDFVVPSLFRVYARDLLLPPSSSELKAGRPEARGSLALDCAPLLRLLGPAPGVSWTAGSPAPAEARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPPGEAAVGLLQFNLSELFSWWIRQGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLFQIFGTGHSSLESPTNMPSPSPDYFTWNLTWIMKDSFPFLSHRSRYGLECSFDFPCELEYSPPLHDLRNQSWSWRRIPSEEASQMDLLDGPGAERSKEMPRGSFLLLNTSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYIAQLLPHNEAAREILLMPTPGKHGWTVLQGRIGRPDNPFRVALEYISSGNRSLSAVDFFALKNCSEGTSPGSKMALQSSFTCWNGTVLQLGQACDFHQDCAQGEDESQMCRKLPVGFYCNFEDGFCGWTQGTLSPHTPQWQVRTLKDARFQDHQDHALLLSTTDVPASESATVTSATFPAPIKSSPCELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAAYEGLSLWQWMVLPLLDVSDRFWLQMVAWWGQGSRAIVAFDNISISLDCYLTISGEDKILQNTAPKSRNLFERNPNKELKPGENSPRQTPIFDPTVHWLFTTCGASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIWKVPATDTYSISGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKDDMLYILVGQQGEDACPSTNQLIQKVCIGENNVIEEEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLENNSSVLGLNGNSGAAGGGGGWNDNTSLLWAGKSLQEGATGGHSCPQAMKKWGWETRGGFGGGGGGCSSGGGGGGYIGGNAASNNDPEMDGEDGVSFISPLGILYTPALKVMEGHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPTPEPHLPLSLILSVVTSALVAALVLAFSGIMIVYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAKKEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQQQGLPLEAATAPGAGHYEDTILKSKNSMNQPGP Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 459127 | ALK | ALK receptor tyrosine kinase | 9598 | VGNC:10681 | Inparanoid, OMA, EggNOG |
| Macaque | 704823 | ALK | ALK receptor tyrosine kinase | 9544 | | OMA, EggNOG |
| Mouse | 11682 | Alk | anaplastic lymphoma kinase | 10090 | MGI:103305 | Inparanoid, OMA, EggNOG |
| Rat | 266802 | Alk | ALK receptor tyrosine kinase | 10116 | RGD:628622 | Inparanoid, OMA, EggNOG |
| Dog | 483021 | ALK | ALK receptor tyrosine kinase | 9615 | VGNC:37802 | Inparanoid, OMA, EggNOG |
| Cow | 536642 | ALK | ALK receptor tyrosine kinase | 9913 | VGNC:25832 | Inparanoid, OMA, EggNOG |
| Pig | 100518423 | ALK | ALK receptor tyrosine kinase | 9823 | | Inparanoid, OMA, EggNOG |
| Opossum | | ALK | ALK receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:427] | 13616 | | Inparanoid, EggNOG |
| Chicken | 421297 | ALK | anaplastic lymphoma receptor tyrosine kinase | 9031 | CGNC:6869 | Inparanoid, OMA |
| Anole lizard | 100553426 | alk | ALK receptor tyrosine kinase | 28377 | | Inparanoid, OMA |
| Zebrafish | 564470 | ltk | leukocyte receptor tyrosine kinase | 7955 | ZDB-GENE-030616-115 | Inparanoid, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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