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PAM

DescriptionPeptidyl-glycine alpha-amidating monooxygenase

Gene and Protein Information

Gene ID5066
Uniprot Accession IDs A6NMR0 A8K293 O43211 O95080 Q16252 Q16253 Q54A45 Q86U53 Q8WVC7 Q9UCG0 PAM
Ensembl ID ENSP00000306100
Symbol PAL PHM
FamilyIn the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.
Sequence
MAGRVPSLLVLLVFPSSCLAFRSPLSVFKRFKETTRPFSNECLGTTRPVVPIDSSDFALDIRMPGVTPKQSDTYFCMSMRIPVDEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNKDCSGVSLHLTRLPQPLIAGMYLMMSVDTVIPAGEKVVNSDISCHYKNYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQSPQLPQAFYPVGHPVDVSFGDLLAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYMEAKHAVSFMTCTQNVAPDMFRTIPPEANIPIPVKSDMVMMHEHHKETEYKDKIPLLQQPKREEEEVLDQGDFYSLLSKLLGEREDVVHVHKYNPTEKAESESDLVAEIANVVQKKDLGRSDAREGAEHERGNAILVRDRIHKFHRLVSTLRPPESRVFSLQQPPPGEGTWEPEHTGDFHMEEALDWPGVYLLPGQVSGVALDPKNNLVIFHRGDHVWDGNSFDSKFVYQQIGLGPIEEDTILVIDPNNAAVLQSSGKNLFYLPHGLSIDKDGNYWVTDVALHQVFKLDPNNKEGPVLILGRSMQPGSDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPLPGQFTVPHSLALVPLLGQLCVADRENGRIQCFKTDTKEFVREIKHSSFGRNVFAISYIPGLLFAVNGKPHFGDQEPVQGFVMNFSNGEIIDIFKPVRKHFDMPHDIVASEDGTVYIGDAHTNTVWKFTLTEKLEHRSVKKAGIEVQEIKEAEAVVETKMENKPTSSELQKMQEKQKLIKEPGSGVPVVLITTLLVIPVVVLLAIAIFIRWKKSRAFGDSEHKLETSSGRVLGRFRGKGSGGLNLGNFFASRKGYSRKGFDRLSTEGSDQEKEDDGSESEEEYSAPLPALAPSSS
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp461974PAMpeptidylglycine alpha-amidating monooxygenase9598VGNC:4116OMA, EggNOG
Macaque707733PAMpeptidylglycine alpha-amidating monooxygenase9544Inparanoid, OMA, EggNOG
Mouse18484Pampeptidylglycine alpha-amidating monooxygenase10090MGI:97475Inparanoid, OMA, EggNOG
Rat25508Pampeptidylglycine alpha-amidating monooxygenase10116RGD:3252Inparanoid, OMA, EggNOG
Dog479145PAMpeptidylglycine alpha-amidating monooxygenase9615VGNC:44250Inparanoid, OMA, EggNOG
Horse791244PAMpeptidylglycine alpha-amidating monooxygenase9796VGNC:21144Inparanoid, OMA, EggNOG
Cow280890PAMpeptidylglycine alpha-amidating monooxygenase9913VGNC:32561Inparanoid, OMA, EggNOG
Pig100526040PAMpeptidylglycine alpha-amidating monooxygenase9823Inparanoid, OMA, EggNOG
Opossum100030601PAMpeptidylglycine alpha-amidating monooxygenase13616Inparanoid, OMA, EggNOG
PlatypusPAMpeptidylglycine alpha-amidating monooxygenase [Source:HGNC Symbol;Acc:HGNC:8596]9258OMA, EggNOG
Chicken427274PAMpeptidylglycine alpha-amidating monooxygenase9031CGNC:11354Inparanoid, OMA, EggNOG
Anole lizard100562563pampeptidylglycine alpha-amidating monooxygenase28377Inparanoid, OMA, EggNOG
Zebrafish570822pampeptidylglycine alpha-amidating monooxygenase7955ZDB-GENE-090313-384Inparanoid, OMA
C. elegans266833pamn-1Probable peptidylglycine alpha-hydroxylating monooxygenase6239Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    oxidoreductase    /    oxygenase    /    Peptidyl-glycine alpha-amidating monooxygenase
DTO Classes
protein    /    Enzyme    /    Oxidoreductase    /    Oxygenase    /    Peptidyl-glycine alpha-amidating monooxygenase

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source
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