AKT2

DescriptionRAC-beta serine/threonine-protein kinase

Gene and Protein Information

Gene ID208
Uniprot Accession IDs B2RBD8 Q05BV0 Q0VAN0 Q0VAN1 Q68GC0
Ensembl ID ENSP00000375892
Symbol PKBB PRKBB HIHGHH PKBBETA RAC-BETA
FamilyBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.
Sequence
MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPMDYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIRE
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp456035AKT2AKT serine/threonine kinase 29598VGNC:10908OMA, EggNOG
Macaque700591AKT2AKT serine/threonine kinase 29544Inparanoid, OMA, EggNOG
Mouse11652Akt2thymoma viral proto-oncogene 210090MGI:104874Inparanoid, OMA, EggNOG
Rat25233Akt2AKT serine/threonine kinase 210116RGD:2082Inparanoid, OMA, EggNOG
Dog449021AKT2AKT serine/threonine kinase 29615VGNC:37772Inparanoid, OMA
Horse100064671AKT2AKT serine/threonine kinase 29796VGNC:15219Inparanoid, OMA
Cow534923AKT2AKT serine/threonine kinase 29913VGNC:25799Inparanoid, OMA
Pig100127478AKT2AKT serine/threonine kinase 29823Inparanoid, OMA
Opossum100014564AKT2AKT serine/threonine kinase 213616Inparanoid, OMA
Anole lizard100555477akt2AKT serine/threonine kinase 228377Inparanoid, OMA
Xenopus100144709akt2v-akt murine thymoma viral oncogene homolog 28364XB-GENE-484168Inparanoid, OMA
Zebrafish378972akt2v-akt murine thymoma viral oncogene homolog 27955ZDB-GENE-031007-5Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    calcium-binding protein    /    non-receptor serine/threonine protein kinase    /    Rac-beta serine/threonine-protein kinase
protein    /    calcium-binding protein    /    transfer/carrier protein    /    Rac-beta serine/threonine-protein kinase
protein    /    calcium-binding protein    /    protein kinase    /    Rac-beta serine/threonine-protein kinase
protein    /    calcium-binding protein    /    calmodulin    /    Rac-beta serine/threonine-protein kinase
protein    /    calcium-binding protein    /    annexin    /    Rac-beta serine/threonine-protein kinase
protein    /    calcium-binding protein    /    transferase    /    Rac-beta serine/threonine-protein kinase
protein    /    calcium-binding protein    /    kinase    /    Rac-beta serine/threonine-protein kinase
DTO Classes
protein    /    Kinase    /    Protein kinase    /    AGC group    /    AKT family    /    Rac-beta serine/threonine-protein kinase

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source