AKT1

DescriptionRAC-alpha serine/threonine-protein kinase

Gene and Protein Information

Gene ID207
Uniprot Accession IDs B2RAM5 B7Z5R1 Q9BWB6
Ensembl ID ENSP00000451828
Symbol PKB RAC AKT PKB RAC CWS6 PRKBA PKB-ALPHA RAC-ALPHA
FamilyBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.
Sequence
MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Macaque697747AKT1AKT serine/threonine kinase 19544Inparanoid, OMA, EggNOG
Mouse11651Akt1thymoma viral proto-oncogene 110090MGI:87986Inparanoid, OMA, EggNOG
Rat24185Akt1AKT serine/threonine kinase 110116RGD:2081Inparanoid, OMA, EggNOG
Dog490878AKT1AKT serine/threonine kinase 19615VGNC:37770Inparanoid, OMA
Horse100061130AKT1AKT serine/threonine kinase 19796VGNC:15217Inparanoid, OMA
Cow280991AKT1AKT serine/threonine kinase 19913VGNC:25797Inparanoid, OMA
Chicken395928AKT1AKT serine/threonine kinase 19031CGNC:49557Inparanoid, OMA
Anole lizard100556289akt1AKT serine/threonine kinase 128377Inparanoid, OMA, EggNOG
Xenopus100490038akt1v-akt murine thymoma viral oncogene homolog 18364XB-GENE-484953Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    calcium-binding protein    /    non-receptor serine/threonine protein kinase    /    Rac-alpha serine/threonine-protein kinase
protein    /    calcium-binding protein    /    transfer/carrier protein    /    Rac-alpha serine/threonine-protein kinase
protein    /    calcium-binding protein    /    protein kinase    /    Rac-alpha serine/threonine-protein kinase
protein    /    calcium-binding protein    /    calmodulin    /    Rac-alpha serine/threonine-protein kinase
protein    /    calcium-binding protein    /    annexin    /    Rac-alpha serine/threonine-protein kinase
protein    /    calcium-binding protein    /    transferase    /    Rac-alpha serine/threonine-protein kinase
protein    /    calcium-binding protein    /    kinase    /    Rac-alpha serine/threonine-protein kinase
DTO Classes
protein    /    Kinase    /    Protein kinase    /    AGC group    /    AKT family    /    Rac-alpha serine/threonine-protein kinase

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source