GPT

DescriptionAlanine aminotransferase 1

Gene and Protein Information

Gene ID2875
Uniprot Accession IDs B0YJ18 D3DWM7 P78398 Q93076 ALT1
Ensembl ID ENSP00000378408
Symbol AAT1 GPT1 AAT1 ALT1 GPT1
FamilyBelongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
Sequence
MASSTGDRSQAVRHGLRAKVLTLDGMNPRVRRVEYAVRGPIVQRALELEQELRQGVKKPFTEVIRANIGDAQAMGQRPITFLRQVLALCVNPDLLSSPNFPDDAKKRAERILQACGGHSLGAYSVSSGIQLIREDVARYIERRDGGIPADPNNVFLSTGASDAIVTVLKLLVAGEGHTRTGVLIPIPQYPLYSATLAELGAVQVDYYLDEERAWALDVAELHRALGQARDHCRPRALCVINPGNPTGQVQTRECIEAVIRFAFEERLFLLADEVYQDNVYAAGSQFHSFKKVLMEMGPPYAGQQELASFHSTSKGYMGECGFRGGYVEVVNMDAAVQQQMLKLMSVRLCPPVPGQALLDLVVSPPAPTDPSFAQFQAEKQAVLAELAAKAKLTEQVFNEAPGISCNPVQGAMYSFPRVQLPPRAVERAQELGLAPDMFFCLRLLEETGICVVPGSGFGQREGTYHFRMTILPPLEKLRLLLEKLSRFHAKFTLEYS
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp472900GPTglutamic--pyruvic transaminase9598VGNC:12192OMA, EggNOG
Macaque703122GPTglutamic--pyruvic transaminase9544Inparanoid, OMA, EggNOG
Mouse76282Gptglutamic pyruvic transaminase, soluble10090MGI:95802Inparanoid, OMA, EggNOG
Rat81670Gptglutamic--pyruvic transaminase10116RGD:621720Inparanoid, OMA, EggNOG
Dog609914GPTglutamic--pyruvic transaminase9615VGNC:41460OMA, EggNOG
Cow539188GPTglutamic--pyruvic transaminase9913VGNC:29616Inparanoid, OMA, EggNOG
Opossum100019438GPTglutamic--pyruvic transaminase13616Inparanoid, OMA
Platypus100089316LOC100089316alanine aminotransferase 19258OMA, EggNOG
Anole lizard100559816LOC100559816alanine aminotransferase 128377Inparanoid, OMA
C. elegans172252C32F10.8hypothetical protein6239OMA, EggNOG
Fruitfly32292CG1640CG1640 gene product from transcript CG1640-RB7227FBgn0030478Inparanoid, EggNOG
S.cerevisiae850778ALT1alanine transaminase ALT14932S000004079Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    transferase    /    transaminase    /    Alanine aminotransferase 1
DTO Classes
protein    /    Enzyme    /    Transferase    /    Transaminase    /    Alanine aminotransferase 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source