AKR1B1

DescriptionAldose reductase

Gene and Protein Information

Gene ID231
Uniprot Accession IDs B2R8N3 Q5U031 Q6FGA4 Q6ICP2 Q9BS21 Q9UCI9 AR
Ensembl ID ENSP00000285930
Symbol ALDR1 AR ADR ALR2 ALDR1
FamilyBelongs to the aldo/keto reductase family.
Sequence
MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPFHEEF
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp737737AKR1B1aldo-keto reductase family 1 member B9598VGNC:13628OMA, EggNOG
Mouse11677Akr1b3aldo-keto reductase family 1, member B3 (aldose reductase)10090MGI:1353494Inparanoid, OMA, EggNOG
Rat24192Akr1b1aldo-keto reductase family 1 member B10116RGD:2092Inparanoid, OMA, EggNOG
Horse100065145AKR1B1aldo-keto reductase family 1 member B9796VGNC:15214Inparanoid, OMA, EggNOG
Cow317748AKR1B1aldo-keto reductase family 1, member B1 (aldose reductase)9913Inparanoid, OMA
Opossum100021757AKR1B1aldo-keto reductase family 1 member B13616Inparanoid, OMA
Platypus100075884LOC100075884aldose reductase-like9258OMA, EggNOG
Anole lizard100564587LOC100564587aldose reductase28377Inparanoid, EggNOG
Xenopus496546akr1b1aldo-keto reductase family 1, member B1 (aldose reductase)8364XB-GENE-5821742OMA, EggNOG
Zebrafish415138akr1b1aldo-keto reductase family 1, member B1 (aldose reductase)7955ZDB-GENE-040625-7Inparanoid, OMA
Zebrafish553452si:dkey-180p18.9si:dkey-180p18.97955ZDB-GENE-041210-132OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    oxidoreductase    /    reductase    /    Aldose reductase
DTO Classes
protein    /    Enzyme    /    Oxidoreductase    /    Reductase    /    Aldose reductase

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source