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HTR1F

Description5-hydroxytryptamine receptor 1F

Gene and Protein Information

Gene ID3355
Uniprot Accession IDs 5-HT-1F
Ensembl ID ENSP00000322924
Symbol HTR1EL 5HT6 MR77 5-HT1F HTR1EL 5-HT-1F
FamilyBelongs to the G-protein coupled receptor 1 family.
Sequence
MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIVSTIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKSVSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRC
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp470863HTR1F5-hydroxytryptamine receptor 1F9598VGNC:53371Inparanoid, OMA, EggNOG
Macaque693418HTR1F5-hydroxytryptamine receptor 1F9544Inparanoid, OMA, EggNOG
Mouse15557Htr1f5-hydroxytryptamine (serotonin) receptor 1F10090MGI:99842Inparanoid, OMA, EggNOG
Rat60448Htr1f5-hydroxytryptamine receptor 1F10116RGD:71083Inparanoid, OMA, EggNOG
Dog100683938HTR1F5-hydroxytryptamine receptor 1F9615VGNC:41826Inparanoid, OMA
Horse100054385HTR1F5-hydroxytryptamine receptor 1F9796VGNC:18902Inparanoid, OMA
Cow407196HTR1F5-hydroxytryptamine receptor 1F9913VGNC:29995Inparanoid, OMA
Pig397187HTR1F5-hydroxytryptamine receptor 1F9823Inparanoid, OMA
Platypus100084719HTR1F5-hydroxytryptamine receptor 1F9258Inparanoid, OMA, EggNOG
Chicken427963HTR1F5-hydroxytryptamine receptor 1F9031CGNC:11551Inparanoid, OMA
Anole lizard100555064htr1f5-hydroxytryptamine receptor 1F28377Inparanoid, OMA
Zebrafish100005344htr1fa5-hydroxytryptamine (serotonin) receptor 1Fa7955ZDB-GENE-081105-125Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    receptor    /    G-protein coupled receptor    /    5-hydroxytryptamine receptor 1f
DTO Classes
protein    /    G-protein coupled receptor    /    Class A rhodopsin like    /    5-hydroxytryptamine receptor    /    5-HT1 receptor    /    5-hydroxytryptamine receptor 1f

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      1.Hoyer, Daniel D, Hannon, Jason P JP and Martin, Graeme R GR. 2002-04 Molecular, pharmacological and functional diversity of 5-HT receptors. [PMID:11888546]
      2.Raymond, J R JR and 7 more authors.Multiplicity of mechanisms of serotonin receptor signal transduction. [PMID:11916537]
      3.Strausberg, Robert L RL and 83 more authors. 2002-12-24 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. [PMID:12477932]
      4.Turecki, G G and 10 more authors. 2003-04-01 Suicide and serotonin: study of variation at seven serotonin receptor genes in suicide completers. [PMID:12627464]
      5.Amlaiky, N N, Ramboz, S S, Boschert, U U, Plassat, J L JL and Hen, R R. 1992-10-05 Isolation of a mouse "5HT1E-like" serotonin receptor expressed predominantly in hippocampus. [PMID:1328180]
      6.Bhatnagar, Anushree A, Sheffler, Douglas J DJ, Kroeze, Wesley K WK, Compton-Toth, BethAnn B and Roth, Bryan L BL. 2004-08-13 Caveolin-1 interacts with 5-HT2A serotonin receptors and profoundly modulates the signaling of selected Galphaq-coupled protein receptors. [PMID:15190056]
      7.Gerhard, Daniela S DS and 115 more authors. 2004-10 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). [PMID:15489334]
      8.Hannula-Jouppi, Katariina K and 6 more authors. 2005-10 The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexia. [PMID:16254601]
      9.Videtic, Alja A and 6 more authors. 2006-09-05 Association study of seven polymorphisms in four serotonin receptor genes on suicide victims. [PMID:16856120]
      10. and Luttrell, Louis M LM. 2008-07 Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors. [PMID:18240029]