APP

DescriptionAmyloid-beta A4 protein

Gene and Protein Information

Gene ID351
Uniprot Accession IDs B2R5V1 B4DII8 D3DSD1 D3DSD2 D3DSD3 P09000 P78438 Q13764 Q13778 Q13793 Q16011 Q16014 Q16019 Q16020 Q6GSC0 Q8WZ99 Q9BT38 Q9UC33 Q9UCA9 Q9UCB6 Q9UCC8 Q9UCD1 Q9UQ58
Ensembl ID ENSP00000284981
Symbol A4 AD1 AAA AD1 PN2 ABPP APPI CVAP ABETA PN-II preA4 CTFgamma
FamilyBelongs to the APP family.
Sequence
MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Show more
Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp473931APPamyloid beta precursor protein9598VGNC:6591Inparanoid, OMA
Mouse11820Appamyloid beta (A4) precursor protein10090MGI:88059Inparanoid, OMA, EggNOG
Rat54226Appamyloid beta precursor protein10116RGD:2139Inparanoid, OMA
Horse100066294APPamyloid beta precursor protein9796VGNC:15428Inparanoid, OMA
Cow280722APPamyloid beta precursor protein9913VGNC:26038OMA, EggNOG
Pig397663APPamyloid beta precursor protein9823Inparanoid, OMA
Opossum100021944APPamyloid beta precursor protein13616Inparanoid, OMA, EggNOG
Chicken374198APPamyloid beta precursor protein9031CGNC:49081Inparanoid, OMA
Anole lizardAPPamyloid beta precursor protein [Source:HGNC Symbol;Acc:HGNC:620]28377Inparanoid, OMA
Xenopus448208appamyloid beta precursor protein8364XB-GENE-479154Inparanoid, OMA
Zebrafish170846appbamyloid beta (A4) precursor protein b7955ZDB-GENE-020220-1Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    protease inhibitor    /    Amyloid-beta A4 protein
DTO Classes
protein    /    Enzyme modulator    /    Protease inhibitor    /    Amyloid-beta A4 protein

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source