| Description | 5-hydroxytryptamine receptor 3A |
|---|
Gene and Protein Information
| Gene ID | 3359 |
|---|---|
| Uniprot Accession IDs | B4DSY6 G5E986 O60854 Q7KZM7 Q99918 Q9BSZ9 5-HT3-A |
| Ensembl ID | ENSP00000347754 |
| Symbol | 5HT3R HTR3 HTR3 5HT3R 5-HT-3 5-HT3A 5-HT3R |
| Family | Belongs to the ligand-gated ion channel (TC 1.A.9) family. 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily. HTR3A sub-subfamily. |
| Sequence | MLLWVQQALLALLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFREFSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQDLQQPVPAWLRHLVLERIAWLLCLREQSTSQRPPATSQATKTDDCSAMGNHCSHMGGPQDFEKSPRDRCSPPPPPREASLAVCGLLQELSSIRQFLEKRDEIREVARDWLRVGSVLDKLLFHIYLLAVLAYSITLVMLWSIWQYA Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 451556 | HTR3A | 5-hydroxytryptamine receptor 3A | 9598 | VGNC:7649 | OMA, EggNOG |
| Macaque | 696912 | HTR3A | 5-hydroxytryptamine receptor 3A | 9544 | Inparanoid, OMA | |
| Mouse | 15561 | Htr3a | 5-hydroxytryptamine (serotonin) receptor 3A | 10090 | MGI:96282 | Inparanoid, OMA, EggNOG |
| Rat | 79246 | Htr3a | 5-hydroxytryptamine receptor 3A | 10116 | RGD:61818 | Inparanoid, OMA, EggNOG |
| Dog | 489399 | HTR3A | 5-hydroxytryptamine receptor 3A | 9615 | VGNC:41829 | Inparanoid, OMA, EggNOG |
| Horse | 100009690 | HTR3A | 5-hydroxytryptamine receptor 3A | 9796 | VGNC:18906 | Inparanoid, OMA, EggNOG |
| Cow | 617674 | HTR3A | 5-hydroxytryptamine receptor 3A | 9913 | VGNC:29998 | Inparanoid, OMA, EggNOG |
| Pig | 100625131 | HTR3A | 5-hydroxytryptamine receptor 3A | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100032164 | HTR3A | 5-hydroxytryptamine receptor 3A | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | 100090306 | HTR3A | 5-hydroxytryptamine receptor 3A | 9258 | Inparanoid, OMA, EggNOG | |
| Chicken | 428247 | HTR3A | 5-hydroxytryptamine receptor 3A | 9031 | CGNC:5284 | Inparanoid, OMA |
| Anole lizard | 100558102 | LOC100558102 | 5-hydroxytryptamine receptor 3A | 28377 | OMA, EggNOG | |
| Xenopus | HTR3A | 5-hydroxytryptamine receptor 3A [Source:HGNC Symbol;Acc:HGNC:5297] | 8364 | OMA, EggNOG | ||
| Zebrafish | 571641 | htr3a | 5-hydroxytryptamine (serotonin) receptor 3A | 7955 | ZDB-GENE-071012-5 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / transporter / ligand-gated ion channel / 5-hydroxytryptamine receptor 3A
protein / transporter / ion channel / 5-hydroxytryptamine receptor 3A
protein / transporter / acetylcholine receptor / 5-hydroxytryptamine receptor 3A
protein / transporter / GABA receptor / 5-hydroxytryptamine receptor 3A
protein / transporter / receptor / 5-hydroxytryptamine receptor 3A
protein / transporter / ligand-gated ion channel / 5-hydroxytryptamine receptor 3A
protein / transporter / ion channel / 5-hydroxytryptamine receptor 3A
protein / transporter / acetylcholine receptor / 5-hydroxytryptamine receptor 3A
protein / transporter / GABA receptor / 5-hydroxytryptamine receptor 3A
protein / transporter / receptor / 5-hydroxytryptamine receptor 3A
DTO Classes
protein / Ion channel / Neurotransmitter receptor, Cys loop, ligand-gated ion channel (LIC) family / 5-hydroxytryptamine receptor subfamily / 5-HT3 receptor sub-subfamily / 5-hydroxytryptamine receptor 3A
protein / Ion channel / Neurotransmitter receptor, Cys loop, ligand-gated ion channel (LIC) family / 5-hydroxytryptamine receptor subfamily / 5-HT3 receptor sub-subfamily / 5-hydroxytryptamine receptor 3A
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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