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EZH2
| Description | Histone-lysine N-methyltransferase EZH2 |
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Gene and Protein Information
| Gene ID | 2146 |
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| Uniprot Accession IDs | B2RAQ1 B3KS30 B7Z1D6 B7Z7L6 Q15755 Q75MG3 Q92857 Q96FI6 |
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| Ensembl ID | ENSP00000320147 |
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| Symbol | KMT6 WVS ENX1 KMT6 WVS2 ENX-1 EZH2b KMT6A |
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| Family | Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. EZ subfamily. |
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| Sequence | MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFPDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 745437 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 9598 | VGNC:4343 | OMA, EggNOG |
| Macaque | 709075 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 14056 | Ezh2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 10090 | MGI:107940 | Inparanoid, OMA, EggNOG |
| Rat | 312299 | Ezh2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 10116 | RGD:1595860 | Inparanoid, OMA, EggNOG |
| Dog | 475511 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 9615 | VGNC:40541 | Inparanoid, OMA, EggNOG |
| Horse | 100051290 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 9796 | VGNC:17750 | Inparanoid, OMA, EggNOG |
| Cow | 509106 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 9913 | VGNC:28675 | Inparanoid, OMA, EggNOG |
| Pig | 100625497 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 9823 | | Inparanoid, OMA, EggNOG |
| Opossum | 100013390 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 13616 | | OMA, EggNOG |
| Platypus | 100073485 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 9258 | | Inparanoid, OMA, EggNOG |
| Anole lizard | 100564989 | ezh2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 28377 | | Inparanoid, OMA |
| Xenopus | | ezh2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:Xenbase;Acc:XB-GENE-956215] | 8364 | | OMA, EggNOG |
| Zebrafish | 768133 | ezh2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 7955 | ZDB-GENE-041111-259 | Inparanoid, OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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