JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

྾

CHEK2

Description	Serine/threonine-protein kinase Chk2

Gene and Protein Information

Gene ID	11200
Uniprot Accession IDs	A8K3Y9 B7ZBF3 B7ZBF4 B7ZBF5 Q6QA03 Q6QA04 Q6QA05 Q6QA06 Q6QA07 Q6QA08 Q6QA10 Q6QA11 Q6QA12 Q6QA13 Q9HBS5 Q9HCQ8 Q9UGF0 Q9UGF1
Ensembl ID	ENSP00000372023
Symbol	CDS1 CHK2 RAD53 CDS1 CHK2 LFS2 RAD53 hCds1 HuCds1 PP1425
Family	Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHK2 subfamily.
Sequence	MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	458733	CHEK2	checkpoint kinase 2	9598	VGNC:12828	OMA, EggNOG
Macaque	713668	CHEK2	checkpoint kinase 2	9544		Inparanoid, OMA, EggNOG
Mouse	50883	Chek2	checkpoint kinase 2	10090	MGI:1355321	Inparanoid, OMA, EggNOG
Rat	114212	Chek2	checkpoint kinase 2	10116	RGD:621543	Inparanoid, OMA, EggNOG
Dog	486338	CHEK2	checkpoint kinase 2	9615	VGNC:39209	Inparanoid, OMA, EggNOG
Horse	100059288	CHEK2	checkpoint kinase 2	9796	VGNC:16493	Inparanoid, OMA, EggNOG
Cow	518897	CHEK2	checkpoint kinase 2	9913	VGNC:27286	Inparanoid, OMA, EggNOG
Opossum	100030584	CHEK2	checkpoint kinase 2	13616		Inparanoid, OMA, EggNOG
Platypus	100077482	CHEK2	checkpoint kinase 2	9258		Inparanoid, OMA, EggNOG
Chicken	768913	CHEK2	checkpoint kinase 2	9031	CGNC:4245	Inparanoid, OMA, EggNOG
Xenopus	100144952	chek2	checkpoint kinase 2	8364	XB-GENE-5765421	Inparanoid, OMA, EggNOG
Zebrafish	336998	chek2	checkpoint kinase 2	7955	ZDB-GENE-030131-8942	Inparanoid, OMA, EggNOG
Fruitfly	35288	lok	loki	7227	FBgn0019686	Inparanoid, EggNOG

DTO Classes
protein / Kinase / Protein kinase / CAMK group / RAD53 family / Serine/threonine-protein kinase chk2

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Name	Specifications	Species reactivity	species	Application	View Details

Name	Disease Type	Mondoid

Data Source	Name	Explore more targets	Explore in Source