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NAE1
| Description | NEDD8-activating enzyme E1 regulatory subunit |
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Gene and Protein Information
| Gene ID | 8883 |
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| Uniprot Accession IDs | A6NCK0 A6NFN4 A8MU28 B2R700 B3KUP9 |
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| Ensembl ID | ENSP00000351990 |
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| Symbol | APPBP1 HPP1 ula-1 APPBP1 A-116A10.1 |
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| Family | Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. |
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| Sequence | MAQLGKLLKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPFPELREHFQSYDLDHMEKKDHSHTPWIVIIAKYLAQWYSETNGRIPKTYKEKEDFRDLIRQGILKNENGAPEDEENFEEAIKNVNTALNTTQIPSSIEDIFNDDRCINITKQTPSFWILARALKEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIGQAPESISEKELKLLCSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIVLYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGMSQTSATFQL Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 467995 | NAE1 | NEDD8 activating enzyme E1 subunit 1 | 9598 | VGNC:9090 | Inparanoid, OMA, EggNOG |
| Macaque | 696429 | NAE1 | NEDD8 activating enzyme E1 subunit 1 | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 234664 | Nae1 | NEDD8 activating enzyme E1 subunit 1 | 10090 | MGI:2384561 | Inparanoid, OMA, EggNOG |
| Rat | 84019 | Nae1 | NEDD8 activating enzyme E1 subunit 1 | 10116 | RGD:619945 | Inparanoid, OMA |
| Dog | 610026 | NAE1 | NEDD8 activating enzyme E1 subunit 1 | 9615 | VGNC:43607 | Inparanoid, OMA, EggNOG |
| Horse | 100065540 | NAE1 | NEDD8 activating enzyme E1 subunit 1 | 9796 | VGNC:20546 | Inparanoid, OMA, EggNOG |
| Cow | 614491 | NAE1 | NEDD8 activating enzyme E1 subunit 1 | 9913 | VGNC:31866 | Inparanoid, OMA, EggNOG |
| Opossum | 100019101 | NAE1 | NEDD8 activating enzyme E1 subunit 1 | 13616 | | Inparanoid, EggNOG |
| Platypus | 100073958 | NAE1 | NEDD8 activating enzyme E1 subunit 1 | 9258 | | Inparanoid, EggNOG |
| Anole lizard | 100556724 | nae1 | NEDD8 activating enzyme E1 subunit 1 | 28377 | | Inparanoid, OMA, EggNOG |
| Xenopus | 100145030 | nae1 | NEDD8 activating enzyme E1 subunit 1 | 8364 | XB-GENE-971667 | Inparanoid, OMA, EggNOG |
| Zebrafish | 573336 | nae1 | nedd8 activating enzyme E1 subunit 1 | 7955 | ZDB-GENE-040426-1552 | Inparanoid, OMA, EggNOG |
| C. elegans | 266650 | ula-1 | NEDD8-activating enzyme E1 regulatory subunit | 6239 | | Inparanoid, OMA |
| Fruitfly | 39244 | APP-BP1 | beta-Amyloid precursor protein binding protein 1 | 7227 | FBgn0261112 | Inparanoid, EggNOG |
| S.cerevisiae | 856104 | ULA1 | Ula1p | 4932 | S000005924 | OMA, EggNOG |
Protein Classes
PANTHER Classes protein /
transfer/carrier protein / NEDD8-activating enzyme E1 regulatory subunit
protein /
ligase / NEDD8-activating enzyme E1 regulatory subunit
DTO Classes protein /
Enzyme /
Ligase / NEDD8-activating enzyme E1 regulatory subunit
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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