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EGFR

DescriptionEpidermal growth factor receptor

Gene and Protein Information

Gene ID1956
Uniprot Accession IDs P00533 O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
Ensembl ID ENSP00000275493
Symbol ERBB ERBB1 HER1 ERBB HER1 mENA ERBB1 PIG61 NISBD2
FamilyBelongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
Sequence
MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp463415EGFRepidermal growth factor receptor9598VGNC:4334OMA, EggNOG
Macaque613027EGFRepidermal growth factor receptor9544OMA, EggNOG
Mouse13649Egfrepidermal growth factor receptor10090MGI:95294Inparanoid, OMA, EggNOG
Rat24329Egfrepidermal growth factor receptor10116RGD:2543Inparanoid, OMA, EggNOG
Dog404306EGFRepidermal growth factor receptor9615VGNC:51866Inparanoid, OMA, EggNOG
Horse100067755EGFRepidermal growth factor receptor9796VGNC:17460Inparanoid, OMA, EggNOG
Cow407217EGFRepidermal growth factor receptor9913VGNC:28366Inparanoid, OMA, EggNOG
Pig397070EGFRepidermal growth factor receptor9823Inparanoid, OMA, EggNOG
Opossum100029625EGFRepidermal growth factor receptor13616Inparanoid, OMA, EggNOG
Platypus100075894EGFRepidermal growth factor receptor9258Inparanoid, OMA, EggNOG
Anole lizard100562231egfrepidermal growth factor receptor28377Inparanoid, OMA
Xenopus100492965egfrepidermal growth factor receptor8364XB-GENE-6067152Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TK group    /    EGFR family    /    Epidermal growth factor receptor

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

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NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

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      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

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