ULK1

DescriptionSerine/threonine-protein kinase ULK1

Gene and Protein Information

Gene ID8408
Uniprot Accession IDs Q9UQ28
Ensembl ID ENSP00000324560
Symbol KIAA0722 ATG1 ATG1A UNC51 hATG1 Unc51.1
FamilyBelongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
Sequence
MEPGRGGTETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPTIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASPSVRKSPPVPVPSYPSSGSGSSSSSSSTSHLASPPSLGEMQQLQKTLASPADTAGFLHSSRDSGGSKDSSCDTDDFVMVPAQFPGDLVAEAPSAKPPPDSLMCSGSSLVASAGLESHGRTPSPSPPCSSSPSPSGRAGPFSSSRCGASVPIPVPTQVQNYQRIERNLQSPTQFQTPRSSAIRRSGSTSPLGFARASPSPPAHAEHGGVLARKMSLGGGRPYTPSPQVGTIPERPGWSGTPSPQGAEMRGGRSPRPGSSAPEHSPRTSGLGCRLHSAPNLSDLHVVRPKLPKPPTDPLGAVFSPPQASPPQPSHGLQSCRNLRGSPKLPDFLQRNPLPPILGSPTKAVPSFDFPKTPSSQNLLALLARQGVVMTPPRNRTLPDLSEVGPFHGQPLGPGLRPGEDPKGPFGRSFSTSRLTDLLLKAAFGTQAPDPGSTESLQEKPMEIAPSAGFGGSLHPGARAGGTSSPSPVVFTVGSPPSGSTPPQGPRTRMFSAGPTGSASSSARHLVPGPCSEAPAPELPAPGHGCSFADPITANLEGAVTFEAPDLPEETLMEQEHTEILRGLRFTLLFVQHVLEIAALKGSASEAAGGPEYQLQESVVADQISLLSREWGFAEQLVLYLKVAELLSSGLQSAIDQIRAGKLCLSSTVKQVVRRLNELYKASVVSCQGLSLRLQRFFLDKQRLLDRIHSITAERLIFSHAVQMVQSAALDEMFQHREGCVPRYHKALLLLEGLQHMLSDQADIENVTKCKLCIERRLSALLTGICA
Show more
Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Macaque709746ULK1unc-51 like autophagy activating kinase 19544Inparanoid, OMA, EggNOG
Mouse22241Ulk1unc-51 like kinase 110090MGI:1270126Inparanoid, OMA, EggNOG
Rat360827Ulk1unc-51 like autophagy activating kinase 110116RGD:1589743Inparanoid, OMA, EggNOG
Dog477437ULK1unc-51 like autophagy activating kinase 19615VGNC:48128Inparanoid, OMA, EggNOG
HorseULK1unc-51 like autophagy activating kinase 1 [Source:HGNC Symbol;Acc:HGNC:12558]9796OMA, EggNOG
Cow526310ULK1unc-51 like autophagy activating kinase 19913VGNC:36658Inparanoid, OMA, EggNOG
Pig100151990ULK1unc-51 like autophagy activating kinase 19823Inparanoid, OMA, EggNOG
Opossum100028481ULK1unc-51 like autophagy activating kinase 113616Inparanoid, OMA, EggNOG
Chicken416800ULK1unc-51 like autophagy activating kinase 19031CGNC:1714Inparanoid, OMA, EggNOG
Anole lizard100561587ulk1unc-51 like autophagy activating kinase 128377Inparanoid, OMA, EggNOG
Xenopus100127200ulk1unc-51 like autophagy activating kinase 18364XB-GENE-492029Inparanoid, OMA, EggNOG
Zebrafish558848ulk1bunc-51 like autophagy activating kinase 17955ZDB-GENE-071203-2Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    non-receptor serine/threonine protein kinase    /    Serine/threonine-protein kinase ulk1
protein    /    protein kinase    /    Serine/threonine-protein kinase ulk1
protein    /    transferase    /    Serine/threonine-protein kinase ulk1
protein    /    kinase    /    Serine/threonine-protein kinase ulk1
DTO Classes
protein    /    Kinase    /    Protein kinase    /    Other group    /    ULK family    /    Serine/threonine-protein kinase ulk1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source