ULK2

DescriptionSerine/threonine-protein kinase ULK2

Gene and Protein Information

Gene ID9706
Uniprot Accession IDs A8MY69 O75119
Ensembl ID ENSP00000378914
Symbol KIAA0623 ATG1B Unc51.2
FamilyBelongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
Sequence
MEVVGDFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQGPVKKSCPVPVPMYSGSVSGSSCGSSPSCRFASPPSLPDMQHIQEENLSSPPLGPPNYLQVSKDSASTSSKNSSCDTDDFVLVPHNISSDHSCDMPVGTAGRRASNEFLVCGGQCQPTVSPHSETAPIPVPTQIRNYQRIEQNLTSTASSGTNVHGSPRSAVVRRSNTSPMGFLRPGSCSPVPADTAQTVGRRLSTGSSRPYSPSPLVGTIPEQFSQCCCGHPQGHDSRSRNSSGSPVPQAQSPQSLLSGARLQSAPTLTDIYQNKQKLRKQHSDPVCPSHTGAGYSYSPQPSRPGSLGTSPTKHLGSSPRSSDWFFKTPLPTIIGSPTKTTAPFKIPKTQASSNLLALVTRHGPAEEQSKDGNEPRECAHCLLVQGSERQRAEQQSKAVFGRSVSTGKLSDQQGKTPICRHQGSTDSLNTERPMDIAPAGACGGVLAPPAGTAASSKAVLFTVGSPPHSAAAPTCTHMFLRTRTTSVGPSNSGGSLCAMSGRVCVGSPPGPGFGSSPPGAEAAPSLRYVPYGASPPSLEGLITFEAPELPEETLMEREHTDTLRHLNVMLMFTECVLDLTAMRGGNPELCTSAVSLYQIQESVVVDQISQLSKDWGRVEQLVLYMKAAQLLAASLHLAKAQIKSGKLSPSTAVKQVVKNLNERYKFCITMCKKLTEKLNRFFSDKQRFIDEINSVTAEKLIYNCAVEMVQSAALDEMFQQTEDIVYRYHKAALLLEGLSRILQDPADIENVHKYKCSIERRLSALCHSTATV
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp454507ULK2unc-51 like autophagy activating kinase 29598VGNC:9768OMA, EggNOG
Macaque710708ULK2unc-51 like autophagy activating kinase 29544Inparanoid, OMA, EggNOG
Mouse29869Ulk2unc-51 like kinase 210090MGI:1352758Inparanoid, OMA, EggNOG
Rat303206Ulk2unc-51 like autophagy activating kinase 210116RGD:1310181Inparanoid, OMA, EggNOG
Dog489525ULK2unc-51 like autophagy activating kinase 29615VGNC:48129Inparanoid, OMA, EggNOG
Horse100073154ULK2unc-51 like autophagy activating kinase 29796VGNC:24785Inparanoid, OMA, EggNOG
Cow618601ULK2unc-51 like autophagy activating kinase 29913VGNC:36659Inparanoid, OMA, EggNOG
Opossum100019989ULK2unc-51 like autophagy activating kinase 213616Inparanoid, OMA, EggNOG
PlatypusULK2unc-51 like autophagy activating kinase 2 [Source:HGNC Symbol;Acc:HGNC:13480]9258OMA, EggNOG
Chicken417614ULK2unc-51 like autophagy activating kinase 29031CGNC:3503Inparanoid, OMA, EggNOG
Anole lizardULK2unc-51 like autophagy activating kinase 2 [Source:HGNC Symbol;Acc:HGNC:13480]28377Inparanoid, OMA, EggNOG
XenopusULK2unc-51 like autophagy activating kinase 2 [Source:HGNC Symbol;Acc:HGNC:13480]8364OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    non-receptor serine/threonine protein kinase    /    Serine/threonine-protein kinase ulk2
protein    /    protein kinase    /    Serine/threonine-protein kinase ulk2
protein    /    transferase    /    Serine/threonine-protein kinase ulk2
protein    /    kinase    /    Serine/threonine-protein kinase ulk2
DTO Classes
protein    /    Kinase    /    Protein kinase    /    Other group    /    ULK family    /    Serine/threonine-protein kinase ulk2

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source